… interleukin 1 (IL-1), pl 7 form, was expressed in Escherichia coli. During purification, IL-1
activity on murine T cells was associated with the recombinant protein. Homogeneous human …

Interleukin 1 (IL 1) is a polypeptide hormone produced by activated macrophages that affects
many different cell types involved in immune and inflammatory responses. The cloning and …

… interleukin 1 (IL-1)3 in local inflammatory responses of blood vessels. Monocyte-derived
and recombinant IL-1 (rIL-1… functions related to blood coagulation (1-4), adhesivity for …

… of biological response modifiers; interleukin 1 (IL 1) induction may be part of the systemic
effects in these therapies. Once released into the circulation, IL 1 acts on multiple target organs …

… Ramadori G, Sipe JD, Dinarello CA, Mizel SB, Colten HR: Pretranslational modulation of
acute phase hepatic protein synthesis by murine recombinant interleukin-1 and purified human …

… Substances that increase nonspecific resistance appear to be able to stimulate mononuclear
phagocytes to synthesize and secrete interleukin 1 (IL-1) in vitro (7). IL-1 is the collective …

… of recombinant human monocyte-derived interleukin 1 … of recombinant monocyte-derived
interleukin 1 receptor antagonist binds to thc 80-kDa IL-1 receptor but does not initiate 1L-1 …

… It has not been possible until now to investigate further the relationship between IL 1 and …
for one murine IL 1 (4). In this report we show that pure recombinant murine IL 1 (rIL 1) is a …

… The availability of recombinant interleukin 1 (IL 1) (5) free of endotoxin and other
cytokines and peptides permits study of the role of the cytokine in radioprotective events. We …

… A phase I study of human recombinant interleukin-1 receptor antagonist (IL-lra) was conducted
in healthy males between the ages of 18 and 30. Twenty-five volunteers received a single…