REGEN-COV antibody combination and outcomes in outpatients with Covid-19

DM Weinreich, S Sivapalasingam… - … England Journal of …, 2021 - Mass Medical Soc
… , REGEN-COV, a combination of the monoclonal antibodies casirivimab … REGEN-COV
has activity in vitro against current severe acute respiratory syndrome coronavirus 2 (SARS-CoV

Subcutaneous REGEN-COV antibody combination to prevent Covid-19

MP O'Brien, E Forleo-Neto, BJ Musser… - … England Journal of …, 2021 - Mass Medical Soc
… evaluate whether subcutaneously administered REGEN-COV could be used … CoV-2. We
used a household-contact trial design to assess whether REGEN-COV could prevent SARS-CoV

[HTML][HTML] Subcutaneous REGEN-COV antibody combination in early asymptomatic SARS-Cov-2 infection: a randomized clinical trial

MP O'Brien, E Forleo-Neto, N Sarkar, F Isa, P Hou… - MedRxiv, 2021 - ncbi.nlm.nih.gov
… Evaluate the efficacy and safety of subcutaneous casirivimab and imdevimab antibody
combination (REGEN-COV) to prevent progression from early asymptomatic SARS-CoV-2 …

[PDF][PDF] The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies

R Copin, A Baum, E Wloga, KE Pascal, S Giordano… - Cell, 2021 - cell.com
… ysis on the spike RBD, where the REGEN-COV antibodies are known to bind and where
all previously identified resistant variants to either antibody are located. Analysis of the RBD …

Effectiveness of REGEN-COV antibody combination in preventing severe COVID-19 outcomes

S Hayek, Y Ben-Shlomo, N Dagan, BY Reis… - Nature …, 2022 - nature.com
REGEN-COV, a combination of the monoclonal antibodies casirivimab and imdevimab, has
been approved as a treatment for high-risk patients infected with SARS-CoV… of REGEN-COV

REGEN-COV antibody cocktail clinical outcomes study in Covid-19 outpatients

DM Weinreich, S Sivapalasingam, T Norton, S Ali… - MedRxiv, 2021 - medrxiv.org
… to patients who were serum antibody-negative and had these … of REGEN-COV, regardless
of baseline serum antibody status… combinations of non-competing antibodies, such as REGEN-…

REGEN-COV Antibody Combination in Outpatients With COVID-19–Phase 1/2 Results

T Norton, S Ali, S Sivapalasingam, H Gao, R Bhore… - medRxiv, 2021 - medrxiv.org
… 7 was significantly greater in the REGEN-COV combined 2400mg+8000mg group versus …
serum antibody–negative patients and in the overall population, respectively. REGEN-COV

[PDF][PDF] Subcutaneous REGEN-COV Antibody Combination to Prevent Covid-19 [published online ahead of print, 2021 Aug 4]

MP O'Brien, E Forleo-Neto… - N Engl J …, 2021 - jaykolasinac.commons.gc.cuny.edu
… heard of REGENCOV and … REGEN-COV were seen to have a lower all-cause hospitalization
compared to bamlanivimab at day 28. Is REGEN-COV the holy grail of monoclonal antibody

REGENCOV antibody combination in patients with lymphoproliferative malignancies and SARS‐CoV‐2 infection

Y Bronstein, I Avivi, YC Cohen, E Feigin, C Perry… - …, 2022 - Wiley Online Library
… According to our local treatment protocol, anti-SARS-CoV-2 neutralizing antibody cocktails
… anti-CD20 antibodies, our local protocol allows treatment with REGEN-COV after more than …

Breakthrough omicron COVID-19 infections in patients receiving the REGEN-Cov antibody combination

A Flahault, J Touchard, H Péré, L Ulrich… - Kidney …, 2022 - kidney-international.org
… Green dashed line: cumulative number of REGEN-Cov administrations. Red line: cumulative
number of COVID-19 infections among patients treated with REGEN-Cov in our cohort. …