Effectiveness of REGEN-COV combination monoclonal antibody infusion to reduce the risk of COVID-19 hospitalization in pregnancy: a retrospective cohort study

FB Williams, JA Morgan, A Elmayan, JK Martin… - American Journal of …, 2023 - ajog.org
… When REGEN-COV was issued emergency use authorization in the … antibodies in
pregnant patients, despite their exclusion from efficacy trials.We hypothesized that REGEN-COV

[HTML][HTML] Effectiveness of REGENCOV antibody cocktail against the B. 1.617. 2 (delta) variant of SARS‐CoV‐2: A cohort study

S Banu, M Sasikala, KVL Parsa… - Journal of internal …, 2022 - ncbi.nlm.nih.gov
… In conclusion, REGENCOV antibody cocktail‐treated high‐risk SARS‐CoV‐2 patients
infected with the delta variant showed faster resolution of symptoms along with reduced viral …

Effectiveness of REGEN-COV Antibody Combination in Preventing Severe COVID-19 Outcomes–A Retrospective Cohort Study​

S Hayek, Y Ben Shlomo, N Dagan… - Available at SSRN …, 2022 - papers.ssrn.com
Background: REGEN-COV has been approved as a treatment for high-risk patients infected
with SARS-CoV-2 within 5 days of their diagnosis. We aim to determine the real-world …

Phase 2 dose-ranging study of the virologic efficacy and safety of the combination COVID-19 antibodies casirivimab and imdevimab in the outpatient setting

C Portal-Celhay, E Forleo-Neto, W Eagan, BJ Musser… - medRxiv, 2021 - medrxiv.org
… These results point to a promising therapeutic approach of co-administering the antibodies
1:1 (REGEN-COV ® antibody combination) to reduce both the viral load of SARS-CoV-2 and …

… clearance of 300 day SARS-CoV-2 infection in a subject with B-cell depletion associated prolonged (B-DEAP) COVID by REGEN-COV anti-spike monoclonal antibody …

AC Drouin, MW Theberge, SY Liu, AR Smither… - Viruses, 2021 - mdpi.com
… Thirteen months prior to writing he received two of five cycles of G-benda, a combination of
… Anti-SARS-CoV-2 vaccine was administered in the window where REGEN-COV antibody

REGEN-COV® for Treatment of Hospitalized Patients with Covid-19

S Somersan-Karakaya, E Mylonakis, VP Menon… - medRxiv, 2021 - medrxiv.org
… As CAS+IMD is a potent antiviral monoclonal antibody combination shown to rapidly reduce
SARS-CoV-2 viral load and modulate a patient’s disease course across various populations …

Compassionate Use of REGEN-COV® in Patients With Coronavirus Disease 2019 (COVID-19) and Immunodeficiency-Associated Antibody Disorders

D Stein, E Oviedo-Orta, WA Kampman… - Clinical Infectious …, 2022 - academic.oup.com
… In this retrospective analysis of immunodeficient patients granted REGEN-COV under
emergency compassionate use, REGEN-COV treatment was associated with rapid viral clearance …

REGEN-COV protects against viral escape in preclinical and human studies

R Copin, A Baum, E Wloga, KE Pascal, S Giordano… - bioRxiv, 2021 - biorxiv.org
… This study demonstrates that a combination of non-competing antibodies, REGEN-COV,
not only provides full coverage against current variants of concern/interest but also protects …

REGEN-COV® antibody cocktail bioanalytical strategy: comparison of LC-MRM-MS and immunoassay methods for drug quantification

SC Irvin, S Ganguly, R Weiss, C Elango, X Zhong… - Bioanalysis, 2021 - Taylor & Francis
combination are used as high, mid and low quality controls. … effective therapies such as
REGEN-COV will remain [Citation… new anti-SARS-CoV-2 spike antibodies, we have successfully …

Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

RECOVERY Collaborative Group, PW Horby… - Medrxiv, 2021 - medrxiv.org
REGEN-COV is a combination of 2 monoclonal antibodies (… We aimed to evaluate the
efficacy and safety of REGEN-COV … plus a single dose of REGEN-COV 8g (casirivimab 4g and …