REGEN-COV antibody combination and outcomes in outpatients with Covid-19

DM Weinreich, S Sivapalasingam… - … England Journal of …, 2021 - Mass Medical Soc
… In the phase 3 portion of an adaptive trial, we randomly assigned outpatients with Covid-19
and risk factors for severe disease to receive various doses of intravenous REGEN-COV or …

REGEN-COV antibody cocktail clinical outcomes study in Covid-19 outpatients

DM Weinreich, S Sivapalasingam, T Norton, S Ali… - MedRxiv, 2021 - medrxiv.org
… demonstrated efficacy in symptomatic outpatients, where it rapidly reduced viral load and …
of REGEN-COV. Here, we report the primary analysis results of the phase 3 portion of this trial. …

REGEN-COV Antibody Combination in Outpatients With COVID-19–Phase 1/2 Results

T Norton, S Ali, S Sivapalasingam, H Gao, R Bhore… - medRxiv, 2021 - medrxiv.org
… demonstrates potent in vitro neutralizing activity against SARS-CoV-2 VOCs … results (N =
275) from the phase 1/2/3 trial assessing the efficacy and safety of REGEN-COV in outpatients

REGEN-COV® for Treatment of Hospitalized Patients with Covid-19

S Somersan-Karakaya, E Mylonakis, VP Menon… - medRxiv, 2021 - medrxiv.org
outpatients with mild-to-moderate COVID-19, and for post-exposure prophylaxis in the United
States and other jurisdictions [5-7]. In outpatients … associated with SARS-CoV-2 infection in …

Real world utilization of REGEN-COV2 at a community hospital

J Ash, R Leavitt, T Dietrich, S Schritter, J Wells… - The American Journal of …, 2021 - Elsevier
… 2 (SARS-CoV-2), physicians and scientists have searched for an outpatient treatment option
… antibodies that targets the spike protein of SARS-CoV-2, was recently given emergency use …

Phase 2 dose-ranging study of the virologic efficacy and safety of the combination COVID-19 antibodies casirivimab and imdevimab in the outpatient setting

C Portal-Celhay, E Forleo-Neto, W Eagan, BJ Musser… - medRxiv, 2021 - medrxiv.org
… This current study evaluates the virologic efficacy and the safety of a range of IV and SC
doses of REGEN-COV in outpatients with asymptomatic SARS-CoV-2 infection, or symptomatic …

Compassionate Use of REGEN-COV® in Patients With Coronavirus Disease 2019 (COVID-19) and Immunodeficiency-Associated Antibody Disorders

D Stein, E Oviedo-Orta, WA Kampman… - Clinical Infectious …, 2022 - academic.oup.com
outpatients with mild-to-moderate COVID-19, no patient experienced symptom progression
or required hospitalization following treatment with REGEN-COV [24]… with REGEN-COV led to …

Outcomes of pregnant patients treated with REGEN-COV during the COVID-19 pandemic

NH Levey, AD Forrest, DW Spielman, KA Easley… - American Journal of …, 2022 - Elsevier
outcomes in pregnant patients who received REGEN-COV and compare these outcomes with
… who tested positive for SARS-CoV-2 but did not receive REGEN-COV. This study aimed to …

Subcutaneous REGEN-COV antibody combination to prevent Covid-19

MP O'Brien, E Forleo-Neto, BJ Musser… - … England Journal of …, 2021 - Mass Medical Soc
… In outpatients with Covid-19, the use of REGEN-COV has been shown to reduce the incidence
of hospitalization or death from any cause by approximately 70%, rapidly reduce the viral …

[HTML][HTML] Subcutaneous REGEN-COV antibody combination in early asymptomatic SARS-Cov-2 infection: a randomized clinical trial

MP O'Brien, E Forleo-Neto, N Sarkar, F Isa, P Hou… - MedRxiv, 2021 - ncbi.nlm.nih.gov
… a trial in symptomatic outpatients at high risk for … REGEN-COV for participants who did
become symptomatic in this study (6 days) was similar to that observed in symptomatic outpatients