R Copin, A Baum, E Wloga, KE Pascal, S Giordano… - bioRxiv, 2021 - biorxiv.org
… effects of antiviral antibody treatment on virus evolution in humans. As predicted by our in vitro and in vivo preclinicalstudies, treatment with the REGEN-COV cocktail in the clinic did not …
… This article addresses why SARS-CoV-2 is so different from … carry the human ACE2 gene for research on SARS-CoV are … therapies and vaccines (clinical and preclinical), COVID-19 trial …
MP O'Brien, E Forleo-Neto, BJ Musser… - … England Journal of …, 2021 - Mass Medical Soc
… RT-qPCR serologic testing at a central laboratory to be negative for SARS-CoV-2 at baseline; … predicted neutralization target concentration (according to preclinical data) as early as the …
DM Weinreich, S Sivapalasingam… - … England Journal of …, 2021 - Mass Medical Soc
… In vitro studies showed that this antibody cocktail, REGEN-COV, retains activity against current … the predicted neutralization target concentration based on in vitro and preclinical data. …
DM Weinreich, S Sivapalasingam, T Norton, S Ali… - MedRxiv, 2021 - medrxiv.org
… In vitro studies demonstrated that REGEN-COV retains activity against current VOCs … preclinicalstudies predict REGEN-COV protection against emergence of viral escape in humans…
S Somersan-Karakaya, E Mylonakis, VP Menon… - medRxiv, 2021 - medrxiv.org
… by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is highly variable; while … morbidity and mortality associated with SARS-CoV-2 infection in hospitalized patients. In a …
MP O'Brien, E Forleo-Neto, N Sarkar, F Isa, P Hou… - MedRxiv, 2021 - ncbi.nlm.nih.gov
… shown consistently in REGEN-COV clinical studies, a larger … concentration, based on in vitro and preclinical data, 19 – 21 on … evidence from phase 3 REGEN-COV clinical studies 24 , 28 …
T Norton, S Ali, S Sivapalasingam, H Gao, R Bhore… - medRxiv, 2021 - medrxiv.org
… The two human sequence antibodies, casirivimab and … SARS-CoV-2 serology testing and central lab PCR testing were … concentration based on in vitro and preclinical data [10-12]. …
… of REGEN‐COV on the delta variant of SARS‐CoV‐2 is … values in patients receiving REGEN‐COV reveals enhanced viral … REGEN‐COV antibody cocktail‐treated high‐risk …