… Over a decade ago, it was proposed that the regulation of tubular repair in the kidney might
… The molecular pathways expressed during normal kidney morphogenesis in the mouse, …

… and mesodermal derivation such as the kidney and brain are thought to he vascularized …
is during embryonic development, and it is in this context that the molecular regulation of …

… kidney development. In this review we will begin by separately discussing these two tales of
tubulogenesis in turn, highlighting the molecular … patterned and is regulated by the cells of …

… is generated, how the inductive signals are regulated and what are their effects on … The
depletion of each of them in the mammalian kidney results in faulty kidney development. Deletion …

… for pH and electrolyte regulation, and … of kidney organoids from hPSCs by assessing the
cells at each step of nephrogenesis has also expanded our knowledge of kidney development. …

… kidney development is also regulated by epigenetic mechanisms. This is essential for
proper development through the various stages of kidney … molecular mechanisms of kidney …

… One outcome of these molecular genetic experiments is that the coordination of … Early
kidney development can thus be seen as a succession of morphogenetic events tightly regulated …

… ontogeny and the major known cellular and molecular mechanisms in control of … The
classic work in the field indicates that kidney organogenesis is regulated by sequential and …

… kidney development, but, in most other cases, we have little idea as to the role of these
molecules, … is a candidate for paracrine regulation of ureteric bud development. Although in-vitro …

… Furthermore, transgenic mice that expressed the Denys-Drash mutant WT1 allele under
the regulation of a podocyte-specific promoter developed glomerular disease.Together, these …