Receptor tyrosine kinases in kidney development

R Song, SS El-Dahr, IV Yosypiv - Journal of signal transduction, 2011 - Wiley Online Library
… The kidney plays a fundamental role in the regulation of arterial blood … and kidney development.
Growth factor ligands bind simultaneously with two cognate cell surface RTK molecules

Wnt signaling in kidney development and disease

Y Wang, CJ Zhou, Y Liu - Progress in molecular biology and translational …, 2018 - Elsevier
… after injury.6, 13 In this chapter, we provide a comprehensive review on the expression,
regulation, and function of Wnt/β-catenin signaling in the context of kidney development and …

From development to cancer: lessons from the kidney to uncover new therapeutic targets

V Dormoy, D Jacqmin, H Lang… - Anticancer research, 2012 - ar.iiarjournals.org
Regulatory molecules involved in nephrogenesis and in RCC and their cellular effects …
various steps of kidney development may later be re-expressed or de-regulated and contribute to …

Renal abnormalities and their developmental origin

A Schedl - Nature Reviews Genetics, 2007 - nature.com
… describe the molecular events that ensure proper kidney induction … genes fulfil various tasks
during development, depending on their … of transcriptional regulators in kidney development. …

Wnt signaling in kidney development and disease

K Pulkkinen, S Murugan, S Vainio - Organogenesis, 2008 - Taylor & Francis
… understanding of the promoting molecular factors, surgery is … an oncogenic potential for
this molecule. HIG2 binds to the … during normal kidney development and is regulated by Wnt …

Growth factor regulation in the nephrogenic zone of the developing kidney

L Oxburgh, SD Muthukrishnan, A Brown - Kidney Development and …, 2017 - Springer
… of these kidneys in culture reveals that the lack of BMP receptor causes an increase in
branching early in kidney development, but a reduction later in development. The molecular basis …

Hox genes and kidney development

DM Wellik - Pediatric nephrology, 2011 - Springer
… , which is essential for regulation of some target genes (… and have very similar molecular
phenotypes. Based on these … proteins operating in the same regulatory network. These data …

Developmental biology of the human kidney

ND Rosenblum - Seminars in Fetal and Neonatal Medicine, 2008 - Elsevier
… differentiation of kidney cells are tightly regulated processes … , cellular and molecular steps
required for kidney formation. … ureteric bud outgrowth to normal kidney development. Foxc1, a …

Evolution, kidney development, and chronic kidney disease

RL Chevalier - Seminars in cell & developmental biology, 2019 - Elsevier
… role of this regulatory system in kidney morphogenesis, homeostasis, and regeneration [11]. …
The rise of molecular genetics has afforded new insight into the evolutionary origins of this …

Notch signaling in kidney development, maintenance, and disease

M Mukherjee, E Fogarty, M Janga, K Surendran - Biomolecules, 2019 - mdpi.com
… from rodent kidney development and injury studies, while discussing human kidney diseases
… epithelial cell states and speculate that Notch activity regulation mediates certain renal …