Planar cell polarity pathway in kidney development, function and disease

E Torban, SY Sokol - Nature Reviews Nephrology, 2021 - nature.com
molecules in normal kidney development and how dysfunction of PCP components may
lead to kidney … that the encoded proteins function as upstream regulators of core PCP genes; …

Molecular anatomy of the kidney: what have we learned from gene expression and functional genomics?

B Rumballe, K Georgas, L Wilkinson, M Little - Pediatric nephrology, 2010 - Springer
… processes involved in kidney development for the last five … of the molecular basis of
kidney development has grown … reveal the molecular markers and regulatory pathways that …

The genetics and epigenetics of kidney development

SR Patel, GR Dressler - Seminars in nephrology, 2013 - Elsevier
… These problems are not unique to kidney development. To understand the biochemical function
… , which can impact how we think about early gene regulation and cell lineage restriction. …

[PDF][PDF] Atlas of gene expression in the developing kidney at microanatomic resolution

EW Brunskill, BJ Aronow, K Georgas, B Rumballe… - Developmental cell, 2008 - cell.com
… provide deeper insight into the genetic regulatory mechanisms of kidney development. …
Development Molecular Anatomy Project), and kidney microarray results are reported here. The …

Transforming growth factor β (TGFβ) and related molecules in chronic kidney disease (CKD)

P Huynh, Z Chai - Clinical Science, 2019 - portlandpress.com
… Transforming growth factor β (TGFβ) has been implicated to be a major regulatory cytokine
in CKD, especially in fibrosis development, and reduced TGFβ signalling activity has been …

Semaphorins in kidney development and disease: modulators of ureteric bud branching, vascular morphogenesis, and podocyte-endothelial crosstalk

K Reidy, A Tufro - Pediatric nephrology, 2011 - Springer
… their receptors is regulated during kidney development. Gain- … kidney vascular patterning
acting as a negative regulator of … complexes can include cell adhesion molecules, such as L1 […

Representing kidney development using the gene ontology

Y Alam-Faruque, DP Hill, EC Dimmer, MA Harris… - PLoS …, 2014 - journals.plos.org
… experiments investigating molecular mechanisms of kidney function and development and
… factors are similarly known to be important regulators of kidney development [36], with PAX2 …

The Wnt/JNK signaling target gene alcam is required for embryonic kidney development

W Cizelsky, A Tata, M Kühl, SJ Kühl - Development, 2014 - journals.biologists.com
… At the molecular level, we found alcam to be regulated by Fzd3 signaling. Our data strongly
support earlier findings (Gessert et al., 2008; Lapointe et al., 2012; Prieve and Moon, 2003), …

The cell adhesion molecule L1 is developmentally regulated in the renal epithelium and is involved in kidney branching morphogenesis

H Debiec, EI Christensen, PM Ronco - The Journal of cell biology, 1998 - rupress.org
… To identify novel morphoregulatory molecules possibly involved in kidney development, we
generated a murine monoclonal antibody (mAb) against a cell surface antigen of the CD cell …

HDAC inhibitors in kidney development and disease

LL Brilli, LM Swanhart, MP de Caestecker… - Pediatric …, 2013 - Springer
… of the ureteric bud during kidney morphogenesis. Taken together, … regulation during
metanephric kidney development. … the up-regulation of p21 [17], these small molecules are also …