… 3 above, much of our knowledge on the molecular regulation of kidney development has
been derived from the analysis of genetically altered or knock-out mice. Gene inactivation in …

… as it is for embryonic kidney development. Decreasing the activity … the development of fibrosis
in chronic kidney disease. … the complex molecular processes involved in and regulated by …

… has multiple functions in development, cell differentiation and proliferation, and regulation
of … signaling pathway playing a role in kidney development, is repressed in the adult but is …

… regulators of the process, including the transcription factors WT1 and Sall1 and the Pax2/Eya/Six
network (4, 15, 20). Kidney development … the molecules involved in kidney development …

… and drivers of early kidney development 4 , that have been essential for the … kidney
development 44 . Of the identified interactions, many were related to stroma-secreted molecules …

… regulated inflammatory processes have an impact on renal recovery and fibrosis. Close scrutiny
of cellular and molecular pathways in repairing human kidneys … with development of the …

… Thus, a better understanding of the cellular and molecular mechanisms … regulated to
ensure normal epithelial differentiation of nephron progenitors during kidney development…

… are expressed in the developing kidney. Several studies have … the IIIc isoform) in kidney
mesenchyme are critical for early MM … Loss of Fgfr2 in the MM leads to many kidney and urinary …

… in the regulation of kidney development and can impinge … molecular targets not been. It
remains to be discovered when the maternal diet influences kidney development, what molecular …

… Our results provide insight into molecular mechanisms that … In the developing kidney,
BMP4 is highly expressed in … mesenchyme in the developing kidney regulated by Wnt-4. …