Genomics has revolutionized the research on fungal secondary metabolite (SM)
biosynthesis. To elucidate the molecular and enzymatic mechanisms underlying the …

Sequencing of fungal genomes and systematic genome mining concerning so far
undiscovered secondary metabolite (SM) gene clusters have uncovered the great potential …

Fungi produce an impressive array of secondary metabolites (SMs) including mycotoxins,
antibiotics and pharmaceuticals. The genes responsible for their biosynthesis, export, and …

Filamentous fungi produce a vast number of bioactive secondary metabolites (SMs), some of
which have found applications in the pharmaceutical industry including as antibiotics and …

Fungi are prolific producers of secondary metabolites (SMs) that show a variety of biological
activities. Recent advances in genome sequencing have shown that fungal genomes harbor …

The accelerating pace of microbial genomics is sparking a renaissance in the field of natural
products research. Researchers can now get a preview of the organism's secondary …

Secondary metabolites (SMs) produced by filamentous fungi possess diverse bioactivities
that make them excellent drug candidates. Whole genome sequencing has revealed that …

Secondary metabolites are produced mostly by clustered genes that are essential to their
biosynthesis. The transcriptional expression of these genes is often cooperatively regulated …

Bacterial and fungal secondary metabolism is a rich source of novel bioactive compounds
with potential pharmaceutical applications as antibiotics, anti-tumor drugs or cholesterol …

Recent advancements in genome sequencing and bioinformatic analysis of fungal genomes
have revealed that fungi possess cryptic or silent biosynthetic gene clusters (BGCs). This …