Tissues are heterogeneous with respect to cellular and non-cellular components and in the
dynamic interactions between these elements. To study the behaviour and fate of individual …

Intravital multiphoton microscopy is widely used to assess the structure and function of
organs in live animals. Although different tissues vary in their accessibility for intravital …

Intravital multiphoton microscopy has opened a new era in the field of biological imaging.
Focal excitation of fluorophores by simultaneous attack of multiple (normally “two”) photons …

Standard multiphoton laser scanning microscopy (MPLSM) has revolutionized our view of
physiologic and pathologic processes in living organisms by enlightening different aspects …

Intravital microscopy (IVM) allows for the direct in vivo visualization of dynamic biological
processes in their physiological context at high spatial and temporal resolution. Novel …

Initially used mainly in the neurosciences, two‐photon microscopy has become a powerful
tool for the analysis of immunological processes. Here, we describe currently available two …

Intravital multiphoton microscopy has become one of the central tools used in the
investigation of dynamic cellular activity and function in living animals under nearly …

Recent advances in photonics, particularly multi-photon microscopy (MPM) and new
molecular and genetic tools are empowering immunologists to answer longstanding …

Background Cancer is a highly complex disease, which involves the cooperation of tumor
cells with multiple types of host cells and the extracellular matrix. Cancer studies that rely …

Highly motile and functionally diverse immune cells orchestrate effective immune responses
through complex and dynamic cooperative behavior. Multiphoton intravital microscopy (MP …