Microglia are the resident macrophages of the central nervous system (CNS). They have
important physiological functions in maintaining tissue homeostasis but also contribute to …

Microglia are the resident immune cells that constantly survey the central nervous system.
They can adapt to their environment and respond to injury or insult by altering their …

Highlights•BAMs are phenotypically and ontogenically distinct from parenchymal
microglia.•BAMs are strategically placed to protect the border regions of the CNS.•Single …

Microglia, the tissue macrophages of the brain, have under healthy conditions a resting
phenotype that is characterized by a ramified morphology. With their fine processes …

Microglia are the resident immune effector cells of the central nervous system (CNS) rapidly
reacting to any perturbation in order to maintain CNS homeostasis. Although their …

Microglia, the only nonneuroepithelial cells found in the parenchyma of the CNS, originate
during embryogenesis from the yolk sac and enter the CNS quite early (embryonic day 9.5 …

The pro-inflammatory immune response driven by microglia is a key contributor to the
pathogenesis of several neurodegenerative diseases. Though the research of microglia …

Inflammation is a series of processes designed for eventual clearance of pathogens and
repair of damaged tissue. In the context of autoimmune recognition, inflammatory processes …

Microglia, the resident immune cells of the mammalian central nervous system (CNS), play a
pivotal role in both physiological and pathological conditions such as the restoration of CNS …

Microglia constitute the powerhouse of the innate immune system in the brain. It is now
widely accepted that they are monocytic-derived cells that infiltrate the developing brain at …