[HTML][HTML] Natural killer cells in SARS-CoV-2 infection: pathophysiology and therapeutic implications

C Di Vito, F Calcaterra, N Coianiz, S Terzoli… - Frontiers in …, 2022 - frontiersin.org
Natural Killer (NK) cells are lymphocytes of the innate immunity that play a crucial role in the
control of viral infections in the absence of a prior antigen sensitization. Indeed, they display …

Flattening the COVID-19 curve with natural killer cell based immunotherapies

M Market, L Angka, AB Martel, D Bastin… - Frontiers in …, 2020 - frontiersin.org
Natural Killer (NK) cells are innate immune responders critical for viral clearance and
immunomodulation. Despite their vital role in viral infection, the contribution of NK cells in …

NK cells: A double edge sword against SARS-CoV-2

E Masselli, M Vaccarezza, C Carubbi, G Pozzi… - Advances in biological …, 2020 - Elsevier
Natural killer (NK) cells are pivotal effectors of the innate immunity protecting an individual
from microbes. They are the first line of defense against invading viruses, given their …

Friends or foes? The knowns and unknowns of natural killer cell biology in COVID-19 and other coronaviruses in July 2020

C Manickam, S Sugawara, RK Reeves - PLoS pathogens, 2020 - journals.plos.org
The COVID-19 pandemic has caused more than 575,000 deaths worldwide as of mid-July
2020 and still continues globally unabated. Immune dysfunction and cytokine storm …

Natural killer cells in antiviral immunity

NK Björkström, B Strunz, HG Ljunggren - Nature Reviews Immunology, 2022 - nature.com
Natural killer (NK) cells play an important role in innate immune responses to viral infections.
Here, we review recent insights into the role of NK cells in viral infections, with particular …

[HTML][HTML] Natural killer cells and unconventional T cells in COVID-19

NK Björkström, A Ponzetta - Current Opinion in Virology, 2021 - Elsevier
Highlights•NK cells and unconventional T cells are robustly activated in SARS-CoV-2
infection.•Both populations of cells also home to lung tissue during acute infection.•Severe …

Can natural killer cells be a principal player in anti-SARS-CoV-2 immunity?

F Ahmed, DH Jo, SH Lee - Frontiers in immunology, 2020 - frontiersin.org
The spread of the coronavirus disease 2019 (COVID-19) pandemic has led to disastrous
consequences, impacting social, economic, and medical systems, spanning both developed …

Natural killer cell immunotypes related to COVID-19 disease severity

C Maucourant, I Filipovic, A Ponzetta, S Aleman… - Science …, 2020 - science.org
Understanding innate immune responses in coronavirus disease 2019 (COVID-19) is
important to decipher mechanisms of host responses and interpret disease pathogenesis …

SARS-CoV-2 infection impairs NK cell functions via activation of the LLT1-CD161 axis

M Lenart, M Górecka, M Bochenek… - Frontiers in …, 2023 - frontiersin.org
Introduction Natural killer (NK) cells plays a pivotal role in the control of viral infections, and
their function depend on the balance between their activating and inhibitory receptors. The …

Defining the role of natural killer cells in COVID-19

MJ Lee, CA Blish - Nature immunology, 2023 - nature.com
Natural killer (NK) cells are critical effectors of antiviral immunity. Researchers have
therefore sought to characterize the NK cell response to coronavirus disease 2019 (COVID …