Highlights•Histone modifications are highly dynamic in the brain and drive changes in many
behaviors including learning and memory.•Chromatin-associated proteins that interact with …

Recent advances in chromatin biology have identified a role for epigenetic mechanisms in
the regulation of neuronal gene expression changes, a necessary process for proper …

In the past few decades, the field of neuroepigenetics has investigated how the brain
encodes information to form long-lasting memories that lead to stable changes in behaviour …

In recent years spectacular advances in the field of epigenetics have taken place. Multiple
lines of evidence that connect epigenetic regulation to brain functions have been …

Turnover and exchange of nucleosomal histones and their variants, a process long believed
to be static in post-replicative cells, remains largely unexplored in brain. Here, we describe a …

Neurons are dynamic cells that respond and adapt to stimuli throughout their long
postmitotic lives. The structural and functional plasticity of neurons requires the regulated …

Plasticity in gene expression is achieved by a complex array of molecular mechanisms by
which intracellular signaling pathways directly govern transcriptional regulation. In addition …

Postmitotic neurons are subject to a vast array of environmental influences that require the
nuclear integration of intracellular signaling events to promote a wide variety of neuroplastic …

The development and function of neurons require the regulated expression of large
numbers of very specific gene sets. Epigenetic modifications of both DNA and histone …

This brief review focuses on the role of epigenetic mechanisms in plasticity and memory
formation, and their identification as targets of activity-dependent regulation in neurons …