Can the history of empiric antibiotic treatment for neonatal sepsis inform future global trials?

E Sharland, S Qazi, P Heath… - Clinical …, 2022 - clinicalmicrobiologyandinfection …
Antimicrobial resistance is a major threat to the Sustainable Development Goal to reduce
neonatal mortality to 12 per 1000 live births [1]. Current global rates are at 17 per 1000 live …

Antibiotic treatment of suspected and confirmed neonatal sepsis within 28 days of birth: a retrospective analysis

JS Wagstaff, RJ Durrant, MG Newman… - Frontiers in …, 2019 - frontiersin.org
Neonatal sepsis causes significant mortality and morbidity worldwide. Diagnosis is usually
confirmed via blood culture results. Blood culture sepsis confirmation can take days and …

[引用][C] Prophylactic antibiotic administration in pregnancy to prevent infectious morbidity and mortality (Cochrane Review)

J Thinkhamrop, GJ Hofmeyr, O Adetoro, P Lumbiganon - The Cochrane Library, 2005

Potential antibiotics for the treatment of neonatal sepsis caused by multidrug-resistant bacteria

CA Darlow, RMA da Costa, S Ellis, F Franceschi… - Pediatric Drugs, 2021 - Springer
Neonatal sepsis causes up to an estimated 680,000 deaths annually worldwide,
predominantly in low-and middle-income countries (LMICs). A significant and growing …

Fetal and neonatal death from maternally acquired infection

Embleton - Paediatric and perinatal epidemiology, 2001 - Wiley Online Library
Infection is a potentially preventable cause of perinatal mortality but there is only limited
epidemiological information on which to develop prophylactic guidelines. The aim of this …

Antibioprophylaxie en obstétrique

H Fernandez, Y Ville, P Bourget - Médecine et Maladies Infectieuses, 1994 - Elsevier
Materno-foetal infection is one of the commonest complications in obstetrics. Prophylactic
antibiotics could improve the prognosis of preterm premature rupture of the membranes …

Optimizing the use of antibacterial agents in the neonatal period

JB Cantey - Pediatric Drugs, 2016 - Springer
Antibiotics are invaluable in the management of neonatal infections. However, overuse or
misuse of antibiotics in neonates has been associated with adverse outcomes, including …

Timing of prophylactic antibiotic administration in the uninfected laboring gravida: a randomized clinical trial

BD Thigpen, WA Hood, S Chauhan, L Bufkin… - American journal of …, 2005 - Elsevier
OBJECTIVE: The purpose of this prospective study was to determine whether the timing of
prophylactic antibiotics at cesarean delivery influences maternal/neonatal infectious …

Antibiotic stewardship for early-onset sepsis

MW Kuzniewicz, KM Puopolo - Seminars in Perinatology, 2020 - Elsevier
Antibiotics are administered to the vast majority of preterm newborns and to a substantial
proportion of term infants in the hours after birth due to risk for early-onset sepsis. The …

Antibiotic use in pregnancy

JS Dashe, LC Gilstrap III - Obstetrics and gynecology clinics of North …, 1997 - Elsevier
Infections are common during pregnancy, and a significant number of pregnant women are
exposed to antibiotics. Urinary tract infections such as bacteriuria, cystitis, and pyelonephritis …