At its most basic level, the function of mammalian sleep can be described as a restorative
process of the brain and body; recently, however, progressive research has revealed a host …

Extraordinary strides have been made toward understanding the complexities and
regulatory mechanisms of sleep over the past two decades thanks to the help of rapidly …

Sleep is a complex physiological process that is regulated globally, regionally, and locally
by both cellular and molecular mechanisms. It occurs to some extent in all animals, although …

Humans have been fascinated by sleep for millennia. After almost a century of scientific
interrogation, significant progress has been made in understanding the neuronal regulation …

Sleep remains one of the most mysterious yet ubiquitous animal behaviors. We review
current perspectives on the neural systems that regulate sleep/wake states in mammals and …

Sleep is a physiological global state composed of two different phases: Non‑rapid eye
movement (NREM) and rapid eye movement (REM) sleep. The control mechanisms of sleep …

Although considered an inactive state for centuries, sleep entails many active processes
occurring at the cellular, circuit and organismal levels. Over the last decade, several key …

Many mammalian species, including humans, spend a substantial fraction of their life
sleeping. Sleep deprivation in rats ultimately leads to death, indicating the essential role of …

This mini-review article presents the remarkable progress that has been made in the past
decade in our understanding of the neural circuitry underlying the regulation of sleep-wake …

Molecular and genetic approaches in several species have provided new insights into the
mechanisms of rest-activity and sleep-wake regulation. Many of these discoveries are …