The acquisition and retrieval of contextual fear memory requires coordinated neural activity
in the hippocampus, medial prefrontal cortex (mPFC), and amygdala. The contextual …

In contextual fear conditioning, experimental subjects learn to associate a neutral context
with an aversive stimulus and display fear responses to a context that predicts danger …

Considerable work emphasizes a role for hippocampal circuits in governing contextual fear
discrimination. However, the intra-and extrahippocampal pathways that route contextual …

The hippocampus can be divided into distinct segments that make unique contributions to
learning and memory. The dorsal segment supports cognitive processes like spatial learning …

Abstract Ventral hippocampal CA1 (vCA1) projections to the amygdala are necessary for
contextual fear memory. Here we used in vivo Ca2+ imaging in mice to assess the temporal …

Anxiety, trauma and stress-related disorders are often characterized by a loss of context-
appropriate emotional responding. The contextual retrieval of emotional memory involves …

Although the circuit mediating contextual fear conditioning has been extensively described,
the precise contribution that specific anatomical nodes make to behavior has not been fully …

Over the past years, numerous studies have provided a clear understanding of the neuronal
circuits and mechanisms involved in the formation, expression and extinction phases of …

Contextual fear memory becomes less context-specific over time, a phenomenon referred to
as contextual fear generalization. Overgeneralization of contextual fear memory is a core …

Many lines of evidence suggest that a reciprocally interconnected network comprising the
amygdala, ventral hippocampus (vHC), and medial prefrontal cortex (mPFC) participates in …