Macrophage migration inhibitory factor is a critical mediator of severe acute pancreatitis
Y Sakai, A Masamune, A Satoh, J Nishihira… - Gastroenterology, 2003 - Elsevier
Background & Aims: Macrophage migration inhibitory factor (MIF), originally described as an
inhibitor of the random migration of macrophages, has been shown recently to be involved …
inhibitor of the random migration of macrophages, has been shown recently to be involved …
Macrophage migration inhibitory factor is an important mediator in the pathogenesis of gastric inflammation in rats
Background & Aims: Macrophage migration inhibitory factor (MIF) has been shown to play a
pivotal role in inflammatory and immune-mediated diseases. This study investigates the role …
pivotal role in inflammatory and immune-mediated diseases. This study investigates the role …
Serum macrophage migration inhibitory factor is an early marker of pancreatic necrosis in acute pancreatitis
SH Rahman, KV Menon, JHM Holmfield… - Annals of …, 2007 - journals.lww.com
Objective: To determine if 24-hour blood concentrations of macrophage migration inhibitory
factor (MIF), soluble CD14, and CD163 receptors could predict complications associated …
factor (MIF), soluble CD14, and CD163 receptors could predict complications associated …
Role of macrophage migration inhibitory factor in acute lung injury in mice with acute pancreatitis complicated by endotoxemia
N Matsuda, J Nishihira, Y Takahashi… - American journal of …, 2006 - atsjournals.org
Acute pancreatitis accompanied by a subsequent infectious attack can often lead to
multisystem organ dysfunction, including acute lung injury (ALI), but the molecular …
multisystem organ dysfunction, including acute lung injury (ALI), but the molecular …
Lack of macrophage migration inhibitory factor protects mice against concanavalin A‐induced liver injury
H Nakajima, H Takagi, N Horiguchi, M Toyoda… - Liver …, 2006 - Wiley Online Library
Background: Macrophage migration inhibitory factor (MIF) is involved in inflammatory and
immune‐mediated diseases but the role of MIF in liver injury has not yet been elucidated …
immune‐mediated diseases but the role of MIF in liver injury has not yet been elucidated …
Pathophysiological roles of macrophage migration inhibitory factor in gastrointestinal, hepatic, and pancreatic disorders
T Ohkawara, J Nishihira, H Takeda, M Asaka… - Journal of …, 2005 - Springer
Macrophage migration inhibitory factor (MIF) is a unique protein, participating in
inflammation, immune response, and cell growth. MIF was first discovered as a lymphokine …
inflammation, immune response, and cell growth. MIF was first discovered as a lymphokine …
Increased serum levels of macrophage migration inhibitory factor in alcoholic liver diseases and their expression in liver tissues
T Kumagi, F Akbar, N Horiike, M Onji - Clinical biochemistry, 2001 - Elsevier
Objectives: To study the role of macrophage migration inhibitory factor (MIF) in the
pathogenesis of alcoholic liver diseases. Design and Methods: The levels of MIF in the sera …
pathogenesis of alcoholic liver diseases. Design and Methods: The levels of MIF in the sera …
[PDF][PDF] Prevention of lethal acute hepatic failure by antimacrophage migration inhibitory factor antibody in mice treated with bacille Calmette‐Guerin and …
S Kobayashi, J Nishihira, S Watanabe, S Todo - Hepatology, 1999 - Wiley Online Library
During the past few years, the biological functions of macrophage migration inhibitory factor
(MIF) have been extensively re‐evaluated. This has been found to be protein involved in …
(MIF) have been extensively re‐evaluated. This has been found to be protein involved in …
Macrophage migration inhibitory factor in the sera and at the colonic mucosa in patients with ulcerative colitis: clinical implications and pathogenic significance
H Murakami, SKMDF Akbar, H Matsui… - European journal of …, 2001 - Wiley Online Library
Background Inflammatory cytokines produced by activated macrophages are implicated in
the pathogenesis of ulcerative colitis (UC). With the theory that macrophage migration …
the pathogenesis of ulcerative colitis (UC). With the theory that macrophage migration …
Transgenic over-expression of macrophage migration inhibitory factor renders mice markedly more susceptible to experimental colitis
T Ohkawara, K Miyashita, J Nishihira… - Clinical & …, 2005 - academic.oup.com
Enhanced production of macrophage migration inhibitory factor (MIF) is recognized in
patients with inflammatory bowel disease (IBD) and mice with experimental colitis; however …
patients with inflammatory bowel disease (IBD) and mice with experimental colitis; however …