The genome-wide supported microRNA-137 variant predicts phenotypic heterogeneity within schizophrenia
We examined the influence of the genome-wide significant schizophrenia risk variant
rs1625579 near the microRNA (miRNA)-137 (MIR137) gene on well-established sources of …
rs1625579 near the microRNA (miRNA)-137 (MIR137) gene on well-established sources of …
MiR-137-derived polygenic risk: effects on cognitive performance in patients with schizophrenia and controls
Abstract Variants at microRNA-137 (MIR137), one of the most strongly associated
schizophrenia risk loci identified to date, have been associated with poorer cognitive …
schizophrenia risk loci identified to date, have been associated with poorer cognitive …
The impact of genome wide supported microRNA‐137 (MIR137) risk variants on frontal and striatal white matter integrity, neurocognitive functioning, and negative …
Although genome wide association studies have highlighted MicroRNA 137 (MIR137) as a
novel susceptibility gene for schizophrenia, the mechanisms by which MIR137 risk variants …
novel susceptibility gene for schizophrenia, the mechanisms by which MIR137 risk variants …
A comprehensive review of the genetic and biological evidence supports a role for MicroRNA‐137 in the etiology of schizophrenia
K Sakamoto, JJ Crowley - … Journal of Medical Genetics Part B …, 2018 - Wiley Online Library
Since it was first associated with schizophrenia (SCZ) in a 2011 genome‐wide association
study (GWAS), there have been over 100 publications focused on MIR137, the gene …
study (GWAS), there have been over 100 publications focused on MIR137, the gene …
Genome-wide supported variant MIR137 and severe negative symptoms predict membership of an impaired cognitive subtype of schizophrenia
Progress in determining the aetiology of schizophrenia (Sz) has arguably been limited by a
poorly defined phenotype. We sought to delineate empirically derived cognitive subtypes of …
poorly defined phenotype. We sought to delineate empirically derived cognitive subtypes of …
Analyzing the role of microRNAs in schizophrenia in the context of common genetic risk variants
Importance The recent implication of 108 genomic loci in schizophrenia marked a great
advancement in our understanding of the disease. Against the background of its polygenic …
advancement in our understanding of the disease. Against the background of its polygenic …
Polymorphisms in MIR137HG and microRNA-137-regulated genes influence gray matter structure in schizophrenia
Evidence suggests that microRNA-137 (miR-137) is involved in the genetic basis of
schizophrenia. Risk variants within the miR-137 host gene (MIR137HG) influence structural …
schizophrenia. Risk variants within the miR-137 host gene (MIR137HG) influence structural …
A GWAS SNP for schizophrenia is linked to the internal MIR137 promoter and supports differential allele-specific expression
A Warburton, G Breen, VJ Bubb… - Schizophrenia …, 2016 - academic.oup.com
Single nucleotide polymorphisms (SNPs) within the MIR137 gene locus have been shown to
confer risk for schizophrenia through genome-wide association studies (GWAS). The …
confer risk for schizophrenia through genome-wide association studies (GWAS). The …
[HTML][HTML] Transcriptional consequences of schizophrenia candidate miR-137 manipulation in human neural progenitor cells
MIR137, transcribed as the microRNA miR-137, is one of the leading candidate
schizophrenia susceptibility genes to arise from large genome-wide association studies …
schizophrenia susceptibility genes to arise from large genome-wide association studies …
MIR137HG risk variant rs1625579 genotype is related to corpus callosum volume in schizophrenia
Genome-wide association studies implicate the MIR137HG risk variant rs1625579
(MIR137HGrv) within the host gene for microRNA-137 as a potential regulator of …
(MIR137HGrv) within the host gene for microRNA-137 as a potential regulator of …