[HTML][HTML] Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaques

RS Sankhala, KG Lal, JL Jensen, V Dussupt… - Nature …, 2024 - nature.com
The repeat emergence of SARS-CoV-2 variants of concern (VoC) with decreased
susceptibility to vaccine-elicited antibodies highlights the need to develop next-generation …

[HTML][HTML] A SARS-CoV-2 spike ferritin nanoparticle vaccine protects hamsters against Alpha and Beta virus variant challenge

KMG Wuertz, EK Barkei, WH Chen, EJ Martinez… - npj Vaccines, 2021 - nature.com
The emergence of SARS-CoV-2 variants of concern (VOC) requires adequate coverage of
vaccine protection. We evaluated whether a SARS-CoV-2 spike ferritin nanoparticle vaccine …

[HTML][HTML] SARS-CoV-2 ferritin nanoparticle vaccine induces robust innate immune activity driving polyfunctional spike-specific T cell responses

JM Carmen, S Shrivastava, Z Lu, A Anderson… - npj Vaccines, 2021 - nature.com
The emergence of variants of concern, some with reduced susceptibility to COVID-19
vaccines underscores consideration for the understanding of vaccine design that optimizes …

[PDF][PDF] SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity

MG Joyce, WH Chen, RS Sankhala, A Hajduczki… - Cell reports, 2021 - cell.com
The need for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) next-
generation vaccines has been highlighted by the rise of variants of concern (VoCs) and the …

Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques

HAD King, MG Joyce, I Lakhal-Naouar… - Proceedings of the …, 2021 - National Acad Sciences
Emergence of novel variants of the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) underscores the need for next-generation vaccines able to elicit broad and durable …

[HTML][HTML] A SARS-CoV-2 spike ferritin nanoparticle vaccine is protective and promotes a strong immunological response in the cynomolgus macaque coronavirus …

SC Johnston, KM Ricks, I Lakhal-Naouar, A Jay… - Vaccines, 2022 - mdpi.com
The COVID-19 pandemic has had a staggering impact on social, economic, and public
health systems worldwide. Vaccine development and mobilization against SARS-CoV-2 (the …

Efficacy of a broadly neutralizing SARS-CoV-2 ferritin nanoparticle vaccine in nonhuman primates

MG Joyce, HAD King, IE Naouar, A Ahmed… - BioRxiv, 2021 - biorxiv.org
The emergence of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants stresses the continued need for next-generation vaccines that confer broad …

A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates

MG Joyce, HAD King, I Elakhal-Naouar… - Science translational …, 2021 - science.org
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
stresses the continued need for next-generation vaccines that confer broad protection …

[PDF][PDF] Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines

AC Walls, MC Miranda, A Schäfer, MN Pham… - Cell, 2021 - cell.com
Understanding vaccine-elicited protection against SARS-CoV-2 variants and other
sarbecoviruses is key for guiding public health policies. We show that a clinical stage …

Protection against SARS-CoV-2 Omicron BA. 1 variant challenge in macaques by prime-boost vaccination with Ad26. COV2. S and SpFN

J Yu, PV Thomas, K McMahan, C Jacob-Dolan… - Science …, 2022 - science.org
Emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and
waning immunity call for next-generation vaccine strategies. Here, we assessed the …