Molnupiravir in COVID-19: A systematic review of literature

AK Singh, A Singh, R Singh, A Misra - Diabetes & Metabolic Syndrome …, 2021 - Elsevier
Background and aims Molnupiravir is a newer oral antiviral drug that has recently been
tested in COVID-19. We aim to conduct a systematic review of literature to find out the …

Diabetic patients with COVID-19 infection are at higher risk of ICU admission and poor short-term outcome

L Roncon, M Zuin, G Rigatelli, G Zuliani - Journal of Clinical Virology, 2020 - Elsevier
Background The prognostic significance of diabetes mellitus (DM) in patients with
coronavirus 2019 disease (COVID-19) remains unknown. Objectives To assess the risk of …

Nirmatrelvir combined with ritonavir for preventing and treating COVID‐19

S Reis, MI Metzendorf, R Kuehn… - Cochrane Database …, 2023 - cochranelibrary.com
Background Oral nirmatrelvir/ritonavir (Paxlovid) aims to avoid severe COVID‐19 in
asymptomatic people or those with mild symptoms, thereby decreasing hospitalization and …

An open-label randomized controlled trial of the effect of lopinavir/ritonavir, lopinavir/ritonavir plus IFN-β-1a and hydroxychloroquine in hospitalized patients with …

F Ader, N Peiffer-Smadja, J Poissy… - Clinical Microbiology …, 2021 - Elsevier
Objectives We evaluated the clinical, virological and safety outcomes of lopinavir/ritonavir,
lopinavir/ritonavir–interferon (IFN)-β-1a, hydroxychloroquine or remdesivir in comparison to …

Clinical effectiveness of oral antiviral agents in older patients with COVID‐19 based on real‐world data

YW Tsai, JY Wu, TH Liu, MH Chuang… - Journal of medical …, 2023 - Wiley Online Library
Several randomized controlled trials and real‐world cohort studies have demonstrated the
efficacies of nirmatrelvir plus ritonavir (NMV‐r) and molnupiravir (MOV) in at‐risk patients …

Oral antiviral medications for COVID-19

LA Petty, PN Malani - JAMA, 2022 - jamanetwork.com
Twonewantiviralmedications, ritonavir-boostednirmatrelvir (Paxlovid, ie, nirmatrelvir-
ritonavir) and molnupiravir (Lagevrio), are currently availableintheUSunderemergencyuseautho …

Clinical effectiveness of nirmatrelvir plus ritonavir in the treatment of COVID-19 in patients with cirrhosis

WH Hsu, BW Shiau, TH Liu, JY Wu… - Expert Review of Anti …, 2023 - Taylor & Francis
Objectives This retrospective cohort study assessed the clinical effectiveness of
nirmatrelvirplus ritonavir (NMV-r) in treating COVID-19 in patients with liver cirrhosis (LC) …

Real-world use of nirmatrelvir-ritonavir in COVID-19 outpatients during the emergence of Omicron variants BA. 2/BA2. 12.1

NR Aggarwal, KC Molina, LE Beaty, TD Bennett… - Medrxiv, 2022 - medrxiv.org
ABSTRACT Background Ritonavir-boosted Nirmatrelvir (NMV-r), a protease inhibitor with in
vitro activity against SARS-CoV-2, has been shown to reduce risk of progression to severe …

Efficacy of lopinavir–ritonavir combination therapy for the treatment of hospitalized COVID-19 patients: A meta-analysis

J Deng, F Zhou, W Hou, K Heybati, S Ali, O Chang… - Future …, 2022 - Taylor & Francis
Aim: To evaluate the efficacy and safety of lopinavir–ritonavir (LPV/r) therapy in treating
hospitalized COVID-19 patients. Materials & methods: Data from randomized and …

Efficacy and safety of favipiravir plus interferon‐beta versus lopinavir/ritonavir plus interferon‐beta in moderately ill patients with COVID‐19: A randomized clinical trial

M Hassaniazad, H Farshidi… - Journal of Medical …, 2022 - Wiley Online Library
Abstract Favipiravir (FVP), lopinavir/ritonavir (LPV/RTV), and interferon‐beta (INF‐beta) are
considered as potential treatments for COVID‐19. We examined the efficacy and safety of …