The first 2 years of the COVID-19 pandemic were mainly characterized by recurrent
mutations of SARS-CoV-2 Spike protein at residues K417, L452, E484, N501 and P681 …

Since the inception of SARS-CoV-2 in December 2019, many variants have emerged over
time. Some of these variants have resulted in transmissibility changes of the virus and may …

As the global severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
expands, genomic epidemiology and whole genome sequencing are being constantly used …

The SARS-CoV-2 spike protein mediates target recognition, cellular entry, and ultimately the
viral infection that leads to various levels of COVID-19 severities. Positive evolutionary …

Over three years' pandemic of 2019 novel coronavirus disease (COVID-19), multiple
variants and novel subvariants have emerged successively, outcompeted earlier variants …

The COVID-19 pandemic caused by SARS-CoV-2 has affected millions of people since its
beginning in 2019. The propagation of new lineages and the discovery of key mechanisms …

The COVID-19 pandemic, caused by the Severe Acute Respiratory Syndrome Coronavirus 2
(SARS-CoV-2), was declared on March 11, 2020 by the World Health Organization. As of the …

Due to the widespread of the COVID-19 pandemic, the SARS-CoV-2 genome is evolving in
diverse human populations. Several studies already reported different strains and an …

The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …

Here we report a preliminary genomic analysis of SARS-CoV-2 B. 1.1. 28 lineage circulating
in the Brazilian Amazon region and their evolutionary relationship with emerging and …