Since 2010, next‐generation sequencing platforms have laid the foundation to an exciting
phase of discovery in oral microbiology as it relates to oral and systemic health and disease …

The starting point for defining effective treatment protocols is a clear understanding of the
etiology and pathogenesis of a condition. In periodontal diseases, this understanding has …

In the mid-1960s the microbial aetiology of periodontal diseases was introduced based on
classical experimental gingivitis studies. Since then, numerous studies have addressed the …

Despite increasing knowledge on phylogenetic composition of the human microbiome, our
understanding of the in situ activities of the organisms in the community and their …

Wade WG. Has the use of molecular methods for the characterization of the human oral
microbiome changed our understanding of the role of bacteria in the pathogenesis of …

High-throughput 16S rRNA gene sequencing has allowed the characterization of
subgingival microbiome shifts from health to periodontitis identifying health-associated …

Objectives: The application of molecular, mainly 16S ribosomal RNA (rRNA)‐based
approaches enables researchers to bypass the cultivation step and has proven its …

The last decade has witnessed unparalleled advances in our understanding of the
complexity of the oral microbiome and the compositional changes that occur in subgingival …

Periodontal diseases are initiated by bacterial species living in polymicrobial biofilms at or
below the gingival margin and progress largely as a result of the inflammation elicited by …

The landscape in dentistry is changing as emerging studies continue to reveal that
periodontal health impacts systemic health, and vice versa. Population studies, clinical …