Deep sequencing of the oral microbiome reveals signatures of periodontal disease

B Liu, LL Faller, N Klitgord, V Mazumdar, M Ghodsi… - PloS one, 2012 - journals.plos.org
The oral microbiome, the complex ecosystem of microbes inhabiting the human mouth,
harbors several thousands of bacterial types. The proliferation of pathogenic bacteria within …

Molecular analysis of the subgingival microbiota in health and disease

RG Ledder, P Gilbert, SA Huws, L Aarons… - Applied and …, 2007 - Am Soc Microbiol
This investigation provides molecular analyses of the periodontal microbiota in health and
disease. Subgingival samples from 47 volunteers with healthy gingivae or clinically …

Next-generation sequencing approaches to understanding the oral microbiome

E Zaura - Advances in dental research, 2012 - journals.sagepub.com
Until recently, the focus in dental research has been on studying a small fraction of the oral
microbiome—so-called opportunistic pathogens. With the advent of next-generation …

The contribution of the human oral microbiome to oral disease: a review

AG Morrison, S Sarkar, S Umar, STM Lee, SM Thomas - Microorganisms, 2023 - mdpi.com
The oral microbiome is an emerging field that has been a topic of discussion since the
development of next generation sequencing and the implementation of the human …

Microbial signatures of health, gingivitis, and periodontitis

L Abusleme, A Hoare, BY Hong, PI Diaz - Periodontology 2000, 2021 - Wiley Online Library
The subgingival crevice harbors diverse microbial communities. Shifts in the composition of
these communities occur with the development of gingivitis and periodontitis, which are …

Metatranscriptomic analyses of the oral microbiome

AE Duran‐Pinedo - Periodontology 2000, 2021 - Wiley Online Library
Although the composition of the oral human microbiome is now well studied, regulation of
genes within oral microbial communities remains mostly uncharacterized. Current concepts …

Distinct and complex bacterial profiles in human periodontitis and health revealed by 16S pyrosequencing

AL Griffen, CJ Beall, JH Campbell… - The ISME …, 2012 - academic.oup.com
Periodontitis has a polymicrobial etiology within the framework of a complex microbial
ecosystem. With advances in sequencing technologies, comprehensive studies to elucidate …

Microbial transitions from health to disease

S Joseph, MA Curtis - Periodontology 2000, 2021 - Wiley Online Library
Recent advances in our understanding of the microbial populations that colonize the human
mouth, their acquisition, interdependency, and coevolution with the host, bring a different …

Periodontal microbiology and microbial etiology of periodontal diseases: historical concepts and contemporary perspectives

GN Belibasakis, D Belstrøm, S Eick… - Periodontology …, 2023 - Wiley Online Library
This narrative review summarizes the collective knowledge on periodontal microbiology,
through a historical timeline that highlights the European contribution in the global field. The …

Studying the human oral microbiome: challenges and the evolution of solutions

AML Benn, NCK Heng, JM Broadbent… - Australian dental …, 2018 - Wiley Online Library
Since the pioneering work of van Leeuwenhoek in 1684, subsequently built upon by other
renowned microbiologists Robert Koch, Willoughby Miller and GV Black, oral microbiology …