Role of microbial communities in the pathogenesis of periodontal diseases and caries

A Mira, A Simon‐Soro, MA Curtis - Journal of clinical …, 2017 - Wiley Online Library
The microbiological characteristics of both caries and periodontal disease show significant
change from those in health. In both instances, there is evidence of co‐association of …

Changes in periodontal health status are associated with bacterial community shifts as assessed by quantitative 16S cloning and sequencing

PS Kumar, EJ Leys, JM Bryk, FJ Martinez… - Journal of clinical …, 2006 - Am Soc Microbiol
The gingival sulcus contains a complex ecosystem that includes many uncultivated bacteria.
Understanding the dynamics of this ecosystem in transitions between health and disease is …

The oral microbiome in health and disease

WG Wade - Pharmacological research, 2013 - Elsevier
The human mouth harbours one of the most diverse microbiomes in the human body,
including viruses, fungi, protozoa, archaea and bacteria. The bacteria are responsible for the …

Identification of candidate periodontal pathogens and beneficial species by quantitative 16S clonal analysis

PS Kumar, AL Griffen, ML Moeschberger… - Journal of clinical …, 2005 - Am Soc Microbiol
Most studies of the bacterial etiology of periodontitis have used either culture-based or
targeted DNA approaches, and so it is likely that pathogens remain undiscovered. The …

Progress in oral microbiome related to oral and systemic diseases: an update

YH Lee, SW Chung, QS Auh, SJ Hong, YA Lee, J Jung… - Diagnostics, 2021 - mdpi.com
The human oral microbiome refers to an ecological community of symbiotic and pathogenic
microorganisms found in the oral cavity. The oral cavity is an environment that provides …

Subgingival microbiota in health compared to periodontitis and the influence of smoking

AJ Camelo-Castillo, A Mira, A Pico, L Nibali… - Frontiers in …, 2015 - frontiersin.org
The etiology of periodontitis has traditionally been associated to a consortium of three
bacterial species—the so-called “red-complex” of periodontal disease—which has been the …

Dysbiosis revisited: Understanding the role of the oral microbiome in the pathogenesis of gingivitis and periodontitis: A critical assessment

FA Scannapieco… - Journal of …, 2021 - Wiley Online Library
This commentary provides background, historical context, and a critical assessment of the
concept that microbial dysbiosis drives the pathogenesis of periodontal diseases. It is long …

Effects of nonsurgical periodontal therapy on the microbiota.

M Umeda, Y Takeuchi, K Noguchi… - Periodontology …, 2004 - search.ebscohost.com
The microbiologic etiology of periodontal disease has been confirmed by numerous studies
conducted over the years. Periodontal treatment thus focuses on the thorough removal of …

Second era of OMICS in caries research: moving past the phase of disillusionment

MM Nascimento, E Zaura, A Mira… - Journal of dental …, 2017 - journals.sagepub.com
Novel approaches using OMICS techniques enable a collective assessment of multiple
related biological units, including genes, gene expression, proteins, and metabolites. In the …

A practical guide to the oral microbiome and its relation to health and disease

K Krishnan, T Chen, BJ Paster - Oral diseases, 2017 - Wiley Online Library
The oral microbiome is incredibly complex with the average adult harboring about 50–100
billion bacteria in the oral cavity, which represent about 200 predominant bacterial species …