Application of high-throughput sequencing in understanding human oral microbiome related with health and disease

H Chen, W Jiang - Frontiers in microbiology, 2014 - frontiersin.org
The oral microbiome is one of most diversity habitat in the human body and they are closely
related with oral health and disease. As the technique developing, high-throughput …

The personal human oral microbiome obscures the effects of treatment on periodontal disease

K Schwarzberg, R Le, B Bharti, S Lindsay, G Casaburi… - PloS one, 2014 - journals.plos.org
Periodontitis is a progressive disease of the periodontium with a complex, polymicrobial
etiology. Recent Next-Generation Sequencing (NGS) studies of the microbial diversity …

Microbial testing in periodontics: value, limitations and future directions.

LM Shaddox, C Walker - Periodontology 2000, 2009 - search.ebscohost.com
The article focuses on the development of various molecular biology techniques for
detecting bacterial species associated with periodontal disease. Also presented are the …

Environmental factors and periodontal microbiome

N Buduneli - Periodontology 2000, 2021 - Wiley Online Library
Periodontal diseases are chronic inflammatory, multifactorial diseases where the major
triggering factors for disease onset are bacteria and their toxins, but the major part of tissue …

An accurate and efficient experimental approach for characterization of the complex oral microbiota

W Zheng, M Tsompana, A Ruscitto, A Sharma… - Microbiome, 2015 - Springer
Background Currently, taxonomic interrogation of microbiota is based on amplification of
16S rRNA gene sequences in clinical and scientific settings. Accurate evaluation of the …

An appraisal of the role of specific bacteria in the initial pathogenesis of periodontitis

PM Bartold, TE Van Dyke - Journal of clinical periodontology, 2019 - Wiley Online Library
Background Historically, inflammatory periodontal diseases (gingivitis and periodontitis)
have been recognized as being primarily of bacterial origin. Bacteria are necessary for …

Impact of oral microbiome in periodontal health and periodontitis: a critical review on prevention and treatment

M Di Stefano, A Polizzi, S Santonocito… - International journal of …, 2022 - mdpi.com
The skin, oral cavity, digestive and reproductive tracts of the human body harbor symbiotic
and commensal microorganisms living harmoniously with the host. The oral cavity houses …

Gingival tissue transcriptomes identify distinct periodontitis phenotypes

M Kebschull, RT Demmer, B Grün… - Journal of Dental …, 2014 - journals.sagepub.com
The currently recognized principal forms of periodontitis—chronic and aggressive—lack an
unequivocal, pathobiology-based foundation. We explored whether gingival tissue …

New views on periodontal microbiota in special patient categories

J Slots, TE Rams - Journal of clinical periodontology, 1991 - Wiley Online Library
The microorganisms in periodontitis of special patient categories have been only partially
elucidated. The periodontitis microbiota of HIV–infected individuals, cancer patients on …

The subgingival microbiome relationship to periodontal disease in older women

RJ Genco, MJ LaMonte… - Journal of dental …, 2019 - journals.sagepub.com
Understanding of the oral microbiome in relation to periodontal disease in older adults is
limited. The composition and diversity of the subgingival microflora and their oligotypes in …