Clinical trials in metastatic uveal melanoma: Immunotherapy

M Orloff - Ocular Oncology and Pathology, 2021 - karger.com
Background: Uveal melanoma (UM) is a rare subtype of melanoma that generally has a poor
prognosis once it has metastasized. Clinical trials evaluating immune checkpoint inhibitors …

Immunotherapies for the treatment of uveal melanoma—history and future

TE Schank, JC Hassel - Cancers, 2019 - mdpi.com
Background: Uveal melanoma is the most common primary intraocular malignancy among
adults. It is, nevertheless, a rare disease, with an incidence of approximately one case per …

Immunotherapy in uveal melanoma: novel strategies and opportunities for personalized treatment

C Masaoutis, S Kokkali… - Expert opinion on …, 2021 - Taylor & Francis
Introduction Uveal melanoma (UM) is the most common intraocular cancer and represents a
discrete subtype of melanoma. Metastatic disease, which occurs in half of patients, has a …

Immunological backbone of uveal melanoma: is there a rationale for immunotherapy?

E Rossi, G Schinzari, IG Zizzari, BA Maiorano… - Cancers, 2019 - mdpi.com
No standard treatment has been established for metastatic uveal melanoma (mUM).
Immunotherapy is commonly used for this disease even though UM has not been included …

Immunotherapy for uveal melanoma

DW Kim, J Anderson, SP Patel - Melanoma Management, 2016 - Taylor & Francis
Uveal melanoma (UM) is a rare cancer with a high mortality rate. In comparison to
cutaneous melanoma, UM has unique immunological features. Arising in the immune …

Clinical trials in metastatic uveal melanoma: current status

TA Sussman, P Funchain, A Singh - Ocular Oncology and Pathology, 2020 - karger.com
Background: Uveal melanoma is a rare subtype of melanoma. Prognosis and survival rates
for patients with metastatic uveal melanoma remain poor. No current FDA-approved …

Role of immune checkpoint inhibitors and novel immunotherapies in uveal melanoma

V Jindal - Chinese Clinical Oncology, 2018 - cco.amegroups.org
Uveal melanoma (UM) is one of the rare malignancies, which can be lethal despite local
treatment. Treatment options available now can control UM in early stages, but once it …

Immunotherapy for the treatment of uveal melanoma: current status and emerging therapies

KM Komatsubara, RD Carvajal - Current oncology reports, 2017 - Springer
Abstract Purpose of Review Uveal melanoma is a distinct subset of melanoma with a biology
and treatment approach that is unique from that of cutaneous melanoma. Here we will …

Immunotherapy for uveal melanoma-current knowledge and perspectives

S Kaštelan, AG Antunica, LB Oresković… - Current medicinal …, 2020 - ingentaconnect.com
Uveal melanoma is the most prevalent primary intraocular tumour in adults with the
incidence between five and six cases per million people in the United States and Europe …

Immunotherapy for uveal melanoma

MP Breazzano, RW Milam Jr, SA Batson… - International …, 2017 - journals.lww.com
Uveal melanoma is the most common primary intraocular tumor in adults. 1 Before the mid-
20th century, enucleation was the mainstay of treatment for uveal melanoma. Although this …