Silencing of lncRNA PKIA-AS1 attenuates spinal nerve ligation-induced neuropathic pain through epigenetic downregulation of CDK6 expression

JZ Hu, ZJ Rong, M Li, P Li, LY Jiang, ZX Luo… - Frontiers in Cellular …, 2019 - frontiersin.org
Neuropathic pain (NP) is among the most intractable comorbidities of spinal cord injury.
Dysregulation of non-coding RNAs has also been implicated in the development of …

LncRNA Kcnq1ot1relieves neuropathic pain through downregulation of Myd88

D Li, C Yuan, B Zhao, G Cai, Y Xu - International Immunopharmacology, 2023 - Elsevier
Abstract Background Long non-coding RNAs (lncRNAs) have already been documented to
become the therapeutic targets for neuropathic pain. Here, this work focused on exploring …

Identification of IncRNA expression profile in the spinal cord of mice following spinal nerve ligation-induced neuropathic pain

BC Jiang, WX Sun, LN He, DL Cao, ZJ Zhang… - Molecular …, 2015 - journals.sagepub.com
Background Neuropathic pain that caused by lesion or dysfunction of the nervous system is
associated with gene expression changes in the sensory pathway. Long noncoding RNAs …

Knockdown of Linc00052 alleviated spinal nerve ligation‐triggered neuropathic pain through regulating miR‐448 and JAK1

L Wang, K Zhu, B Yang, Y Cai - Journal of Cellular Physiology, 2020 - Wiley Online Library
The dysfunction of the nervous system contributes to neuropathic pain. Long noncoding
RNAs are reported to participate in neuropathic pain. Recently, Linc00052 is implicated to …

LncRNA KCNA2-AS regulates spinal astrocyte activation through STAT3 to affect postherpetic neuralgia

C Kong, J Du, H Bu, C Huang, F Xu, H Ren - Molecular Medicine, 2020 - Springer
Objectives Postherpetic neuralgia (PHN) is the most common complication of herpes zoster,
but the mechanism of PHN is still unclear. Activation of spinal astrocytes is involved in PHN …

[HTML][HTML] Long non-coding RNA CCAT1 modulates neuropathic pain progression through sponging miR-155

L Dou, H Lin, K Wang, G Zhu, X Zou, E Chang, Y Zhu - Oncotarget, 2017 - ncbi.nlm.nih.gov
Neuropathic pain is caused by dysfunction or primary injury of the somatosensory nervous
system. Long noncoding RNAs (lncRNAs) play important roles in the development of …

Functional roles of lncRNAs and its potential mechanisms in neuropathic pain

S Tang, J Zhou, H Jing, M Liao, S Lin, Z Huang… - Clinical …, 2019 - Springer
Neuropathic pain (NP) is ranked as one of the major forms of chronic pain and emerges as a
direct consequence of a lesion or disease affecting the somatosensory nervous system …

Long non-coding RNA LINC01119 promotes neuropathic pain by stabilizing BDNF transcript

L Zhang, H Feng, Y Jin, Y Zhan, Q Han… - Frontiers in Molecular …, 2021 - frontiersin.org
Neuropathic pain (NP) is caused by primary injury or dysfunction of the peripheral and the
central nervous system. Long non-coding RNAs were critical regulators involved in nervous …

Identifying a novel KLF2/lncRNA SNHG12/miR-494-3p/RAD23B axis in Spare Nerve Injury-induced neuropathic pain

J Zhang, H Zhao, A Zhang, C Zhao, Z Mei, H Yao… - Cell death …, 2022 - nature.com
Spinal cord injury (SCI) is a devastating condition for patients, affecting nearly 2.5 million
people globally. Multiple side effects of SCI have resulted in a terrible life experience for SCI …

Identification of the spinal expression profile of non-coding RNAs involved in neuropathic pain following spared nerve injury by sequence analysis

J Zhou, Q Xiong, H Chen, C Yang… - Frontiers in molecular …, 2017 - frontiersin.org
Neuropathic pain (NP) is caused by damage to the nervous system, resulting in aberrant
pain, which is associated with gene expression changes in the sensory pathway. However …