The insulin-like growth factor-2 mRNA-binding proteins 1, 2, and 3 (IGF2BP1, IGF2BP2,
IGF2BP3) belong to a conserved family of RNA-binding, oncofetal proteins. Several studies …

The post-transcriptional control of gene expression mediated by RNA-binding proteins
(RBPs), long non-coding RNAs (lncRNAs) as well as miRNAs is essential to determine …

The insulin-like growth factor-2 mRNA-binding protein 1 (IGF2BP1) plays essential roles in
embryogenesis and carcinogenesis. IGF2BP1 serves as a post-transcriptional fine-tuner …

The insulin-like growth factor-2 mRNA-binding proteins (IGF2BPs) pertain to a highly
conservative RNA-binding family that works as a post-transcriptional fine-tuner for target …

RNA‐binding proteins (RBPs) mediate the localization, stability, and translation of the target
transcripts and fine‐tune the physiological functions of the proteins encoded. The insulin …

RNA network control is a key aspect of proper cellular homeostasis. In this context, RNA-
binding proteins (RBPs) play a major role as regulators of the RNA life cycle due to their …

The six members of the family of insulin-like growth factor (IGF) binding proteins (IGFBPs)
were originally characterized as passive reservoirs of circulating IGFs, but they are now …

The oncofetal IGF2 mRNA binding proteins (IGF2BPs) are upregulated in most cancers but
their paralogue-specific roles in tumor cells remain poorly understood. In a panel of five …

Insulin-like growth factor (IGF) binding protein 2 (IGFBP2) was discovered and identified as
an IGF system regulator, controlling the distribution, function, and activity of IGFs in the …

Insulin-like growth factor binding protein-3 (IGFBP-3) is a p53 tumor suppressor-regulated
protein and a major carrier for IGFs in circulation. Among six high-affinity IGFBPs, which are …