The 5-HT1B receptor: a novel target for the pathophysiology of depression (supplementary tables)
BM Ruf, Z Bhagwagar - Current drug targets, 2009 - ingentaconnect.com
The serotonergic (5-HT) system has been widely implicated in the pathophysiology of Major
Depressive Disorder (MDD). Although the 5-HT system is a popular target for drug therapy in …
Depressive Disorder (MDD). Although the 5-HT system is a popular target for drug therapy in …
5-HT1A receptor function in major depressive disorder
J Savitz, I Lucki, WC Drevets - Progress in neurobiology, 2009 - Elsevier
Dysfunction of the serotonin 1A receptor (5-HT1A) may play a role in the genesis of major
depressive disorder (MDD). Here we review the pharmacological, post-mortem, positron …
depressive disorder (MDD). Here we review the pharmacological, post-mortem, positron …
The 5-HT1A receptor in major depressive disorder
J Kaufman, C DeLorenzo, S Choudhury… - European …, 2016 - Elsevier
Abstract Major Depressive Disorder (MDD) is a highly prevalent psychiatric diagnosis that is
associated with a high degree of morbidity and mortality. This debilitating disorder is …
associated with a high degree of morbidity and mortality. This debilitating disorder is …
Association Study of the 5-HT6 Receptor Polymorphism (C267T) and Symptomatology and Antidepressant Response in Major Depressive Disorders
WH Wu, SJ Huo, CY Cheng, CJ Hong, SJ Tsai - Neuropsychobiology, 2001 - karger.com
The serotonergic neurotransmitter system has been implicated in the pathogenesis of major
depressive disorder (MDD). Of the 14 human serotonin (5-HT) receptors, the 5-HT6 receptor …
depressive disorder (MDD). Of the 14 human serotonin (5-HT) receptors, the 5-HT6 receptor …
5-HT2B receptors are required for serotonin-selective antidepressant actions
The therapeutic effects induced by serotonin-selective reuptake inhibitor (SSRI)
antidepressants are initially triggered by blocking the serotonin transporter and rely on long …
antidepressants are initially triggered by blocking the serotonin transporter and rely on long …
Role of p11 in cellular and behavioral effects of 5-HT4 receptor stimulation
JL Warner-Schmidt, M Flajolet, A Maller… - Journal of …, 2009 - Soc Neuroscience
p11 (S100A10), a member of a large family of S100 proteins, interacts with serotonin
receptor 1B (5-HTR1B), modulates 5-HT1B receptor signal transduction, and is required for …
receptor 1B (5-HTR1B), modulates 5-HT1B receptor signal transduction, and is required for …
5-HT1A autoreceptor regulation and functional polymorphisms that modify the serotonin system and their association with depression and schizophrenia
A Burns - 2006 - ruor.uottawa.ca
The serotonergic system, and in particular the 5-HT1A receptor, are involved in the etiology
and treatment of depression. The hypothesis that antidepressants downregulate 5-HT1A …
and treatment of depression. The hypothesis that antidepressants downregulate 5-HT1A …
5-HT1A receptors, gene repression, and depression: guilt by association
PR Albert, S Lemonde - The Neuroscientist, 2004 - journals.sagepub.com
The serotonin system is implicated in major depression and suicide and is negatively
regulated by somatodendritic 5-HT1A autoreceptors. Desensitization of 5-HT1A …
regulated by somatodendritic 5-HT1A autoreceptors. Desensitization of 5-HT1A …
The 5-HT1B receptor - a potential target for antidepressant treatment
M Tiger, K Varnäs, Y Okubo, J Lundberg - Psychopharmacology, 2018 - Springer
Major depressive disorder (MDD) is the leading cause of disability worldwide. The serotonin
hypothesis may be the model of MDD pathophysiology with the most support. The majority of …
hypothesis may be the model of MDD pathophysiology with the most support. The majority of …
Transcriptional dys-regulation in anxiety and major depression: 5-HT1A gene promoter architecture as a therapeutic opportunity
PR Albert, LM Fiori - Current pharmaceutical design, 2014 - ingentaconnect.com
The etiology of major depression remains unclear, but reduced activity of the serotonin (5-
HT) system remains implicated and treatments that increase 5-HT neurotransmission can …
HT) system remains implicated and treatments that increase 5-HT neurotransmission can …