Site-specific labeling of proteins with a paramagnetic tag is an efficient way to provide
atomic-resolution information about the dynamics, interactions, and structures of the proteins …

Highlights•Anisotropic paramagnetic effects include PseudoContact Shifts and RDC.•PCS
provide long-range restraints for structure determination.•Practical aspects of PCS structure …

Organic synthesis of a ligand with high binding affinities for paramagnetic lanthanide ions is
an effective way of generating paramagnetic effects on proteins. These paramagnetic effects …

Site specific installation of a paramagnetic ion with magnetic anisotropy in a biomolecule
generates valuable structural restraints, such as pseudocontact shifts (PCSs) and residual …

The anisotropic component of the magnetic susceptibility tensor (Δχ tensor) associated with
various paramagnetic metal ions can induce pseudocontact shifts (PCSs) and residual …

Site‐specific labeling of proteins with lanthanide ions offers great opportunities for
investigating the structure, function, and dynamics of proteins by virtue of the unique …

There is increasing interest in the paramagnetic labeling of proteins for structural studies by
NMR spectroscopy. The resulting paramagnetic effects, particularly pseudocontact shifts …

Paramagnetic NMR is a useful technique to study proteins and protein complexes and the
use of paramagnetic relaxation enhancement (PRE) for this purpose has become wide …

Paramagnetic metal ions bound to proteins generate a dipolar field that can be accurately
probed by pseudocontact shifts (PCS) displayed by the protein's nuclear spins. PCS are …

Ligating a protein at a specific site with a tag molecule containing a paramagnetic metal ion
provides a versatile way of generating pseudocontact shifts (PCSs) in nuclear magnetic …