Diagnostic and Prognostic Performance of Metabolic Signatures in Pancreatic Ductal Adenocarcinoma: The Clinical Application of Quantitative NextGen Mass …

P D'Amora, IDCG Silva, SS Evans, AJ Nagourney… - Metabolites, 2024 - mdpi.com
With 64,050 new diagnoses and 50,550 deaths in the US in 2023, pancreatic ductal
adenocarcinoma (PDAC) is among the most lethal of all human malignancies. Early …

Metabolomics in pancreatic cancer biomarkers research

J Tumas, K Kvederaviciute, M Petrulionis, B Kurlinkus… - Medical Oncology, 2016 - Springer
Pancreatic cancer is one of the worst prognoses of all malignancies. More than 40,000
deaths a year from this disease are observed in European Union alone. The only possibly …

[PDF][PDF] Metabolomics analysis of marker metabolites for patients with pancreatic cancer

A Zhang, H Sun, G Yan, Y Han, XJ Wang - Med. Chem, 2014 - scholar.archive.org
Metabolomics is a rapidly growing field of research used in the identification and
quantification of the small molecule metabolites within an organism, thereby providing …

Serum Metabolite Biomarkers for Pancreatic Tumors: Neuroendocrine and Pancreatic Ductal Adenocarcinomas—A Preliminary Study

K Skubisz, K Dąbkowski, E Samborowska… - Cancers, 2023 - mdpi.com
Simple Summary Pancreatic cancer is a significant problem worldwide. Most cancers are
diagnosed at an advanced stage. Limited knowledge of the pathogenesis of pancreatic …

[HTML][HTML] Metabolomic profile in pancreatic cancer patients: a consensus-based approach to identify highly discriminating metabolites

IM Di Gangi, T Mazza, A Fontana, M Copetti, C Fusilli… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Purpose pancreatic adenocarcinoma is the fourth leading cause of cancer related deaths
due to its aggressive behavior and poor clinical outcome. There is a considerable variability …

[HTML][HTML] Metabolomic biomarkers of pancreatic cancer: a meta-analysis study

KY Mehta, HJ Wu, SS Menon, Y Fallah, X Zhong… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Pancreatic cancer (PC) is an aggressive disease with high mortality rates, however, there is
no blood test for early detection and diagnosis of this disease. Several research groups …

Metabolomic profiling for biomarker discovery in pancreatic cancer

P Kaur, K Sheikh, A Kirilyuk, K Kirilyuk, R Singh… - International Journal of …, 2012 - Elsevier
Pancreatic cancer (PC) is the fourth leading cause of cancer death in the United States, with
4% survival, 5 years after diagnosis. Patients with pancreatic cancer are usually diagnosed …

The metabolic time line of pancreatic cancer: Opportunities to improve early detection of adenocarcinoma

HB Moore, R Culp-Hill, JA Reisz, PJ Lawson… - The American Journal of …, 2019 - Elsevier
Background A reliable biomarker to detect pancreatic ductal adenocarcinoma (PDAC)
continues to be elusive. With employing metabolomics we hypothesize that a broader …

Metabolic responses to the occurrence and chemotherapy of pancreatic cancer: biomarker identification and prognosis prediction

T Teng, H Shi, Y Fan, P Guo, J Zhang, X Qiu, J Feng… - Scientific Reports, 2024 - nature.com
As the most malignant tumor, the prognosis of pancreatic cancer is not ideal even in the
small number of patients who can undergo radical surgery. As a highly heterogeneous …

[HTML][HTML] Metabolomics based predictive classifier for early detection of pancreatic ductal adenocarcinoma

K Unger, KY Mehta, P Kaur, Y Wang, SS Menon… - Oncotarget, 2018 - ncbi.nlm.nih.gov
The availability of robust classification algorithms for the identification of high risk individuals
with resectable disease is critical to improving early detection strategies and ultimately …