Background: We postulated that the abundance of various metabolites in blood would
facilitate the diagnosis of pancreatic and biliary lesions, which could potentially prevent …

In their recent article, Kobayashi and colleagues (1) sought to construct and validate a
diagnostic model for pancreatic cancer using gas chromatography-mass spectrometry …

Through metabolic subtyping, metabolic vulnerabilities can be exploited for developing
efficacious treatments. A glycolytic subtype indicates poor survival in patients with pancreatic …

Tumor cells exhibit a specialized metabolism supporting their superior ability for rapid
proliferation, migration, and apoptotic evasion. It is reasonable to assume that the specific …

Metabolite profiles of serum from pancreatic cancer (PC) patients (n= 51) and non-disease
controls (n= 47) were measured using 1H nuclear magnetic resonance (NMR) spectroscopy …

Background Pancreatic cancer is the fourth leading cause of cancer related deaths in the
United States with a five-year survival rate of 6%. It is characterized by extremely aggressive …

To establish a screening strategy for pancreatic cancer (PC) based on new-onset diabetic
mellitus (NO-DM), serum metabolomics analysis and a search for the metabolic pathways …

Pancreatic cancer (PC) is one of the most aggressive malignancies with high mortality due
to a complex and latent pathogenesis leading to the severe lack of early diagnosis methods …

Pancreatic ductal adenocarcinoma (PDA) is a highly lethal cancer with a long-term survival
rate under 10%. Available cytotoxic chemotherapies have significant side effects, and only …

Background Pancreatic cancer (PC) and biliary tract cancer (BTC) are highly aggressive
cancers, characterized by their rarity, difficulty in diagnosis, and overall poor prognosis …