Multiphoton microscopy has enabled biologists to collect high-resolution images hundreds
of microns into biological tissues, including tissues of living animals. While the depth of …

Multiphoton fluorescence microscopy is a powerful, important tool in biomedical research
that offers low photon toxicity and higher spatial and temporal resolution than other in vivo …

Optical microscopy, when applied to living animals, provides a powerful means of studying
cell biology in the most physiologically relevant setting. The ability of two-photon microscopy …

Intravital optical microscopy provides a powerful means of studying the cell biology in the
most physiologically relevant setting. The ability of multiphoton microscopy to collect optical …

In vivo microscopy is a powerful method for studying fundamental issues of physiology and
pathophysiology. The recent development of multiphoton fluorescence microscopy has …

In conventional fluorescence or confocal microscopy, emitted light is generated not only in
the focal plane but also above and below. The situation is different in multiphoton-induced …

Many multiphoton imaging applications would benefit from a larger field of view; however,
large field of views (> mm) require low magnification objectives which have low light …

Multiphoton microscopy has evolved into a powerful bioimaging tool in three dimensions.
However, the ability to image biological specimens in-depth can be hindered by sample …

Multiphoton microscopy is a powerful technique for achieving three‐dimensional submicron
imaging in biological specimens. However, specimen optical parameters such as refractive …

Optimization of illumination and detection optics is pivotal for multiphoton imaging in highly
scattering tissue and the objective lens is the central component in both of these pathways …