Bipolar disorder can be challenging to treat, especially depressive episodes and ultrarapid
cycling presentations. Patients with bipolar disorder take an average of four psychotropic …

Background Bipolar Disorder is a severe psychiatric illness, characterised by mood swings
between mania and depression, with a life time prevalence in the order of 2.4%(Merikangas …

Background Treatment in bipolar disorder (BD) is commonly applied as a multimodal
therapy based on decision algorithms that lack an integrative understanding of molecular …

Background Bipolar disorder (BD) is a psychiatric illness defined by pathological alterations
between the mood states of mania and depression, causing disability, imposing healthcare …

This is a personal perspective on bipolar disorder, entirely written by a well-informed patient
who is a successful mental heath professional. The patient prefers to remain anonymous; …

Many patients require trials of different antidepressants to find a suitable treatment for
depression and anxiety disorders. Pharmacogenomic (PGx) testing may provide …

Background Controlled substance prescription use and abuse in the United States has
become a public health epidemic. Specifically, benzodiazepine abuse in 2013 has …

Globally psychiatric disorders present a major health concern. Currently, innovations in
treatment are limited by (i) lack of biomarkers for symptom change and diagnosis,(ii) …

Background Bipolar disorder (BD) is a frequent cause of disability, health care costs, and
risk of suicide. Pharmacogenetic tests (PGTs) could help clinicians to identify those patients …

The hopes for readily implementable precision medicine are high. For many complex
disorders, such as bipolar disorder, these hopes critically hinge on tangible successes in …