The primary etiological agent for the initiation and progression of periodontal disease is the
dental plaque biofilm which is an organized aggregation of microorganisms residing within a …

Many oral pathologies, such as dental caries, periodontal disease and peri-implantitis are
plaque-related. Dental plaque is a microbial biofilm formed by organisms tightly bound to a …

The nexus between periodontal inflammation and the polymicrobial biofilm in the gingival
sulcus is critical to understanding the pathobiology of periodontitis. Both play a major role in …

In the mid-1960s the microbial aetiology of periodontal diseases was introduced based on
classical experimental gingivitis studies. Since then, numerous studies have addressed the …

Background: Most microorganisms in nature attach to surfaces and form matrix‐embedded
biofilms. Biofilms are highly structured and spatially organized, and are often composed of …

This commentary provides background, historical context, and a critical assessment of the
concept that microbial dysbiosis drives the pathogenesis of periodontal diseases. It is long …

Abstract Background and Aims The scope of this working group was to review (1) ecological
interactions at the dental biofilm in health and disease,(2) the role of microbial communities …

Introduction: Periodontal diseases are the pathological manifestation of the host response
against the bacterial challenge from the dental biofilm at the tooth/gingival interface. The …

This chapter addresses the host responses to the microbial biofilm that constitutes the
subgingival dental plaque. The host response to infection draws upon the innate …

Background The mouth supports a diverse microbiota which exists as structurally-organised
biofilms on mucosal and dental surfaces. The oral microbiota provides major benefits to the …