What controls the optical properties of DNA-linked gold nanoparticle assemblies?

JJ Storhoff, AA Lazarides, RC Mucic… - Journal of the …, 2000 - ACS Publications
A study aimed at understanding the factors that control the optical properties of DNA-linked
gold nanoparticle aggregates containing oligonucleotide linkers of varying length (24− 72 …

The DNA-mediated formation of supramolecular mono-and multilayered nanoparticle structures

TA Taton, RC Mucic, CA Mirkin… - Journal of the American …, 2000 - ACS Publications
Herein, we report a new, noncovalent DNA-based strategy for controlling the stepwise
growth of layered nanoparticle structures off of glass surfaces. Others have demonstrated …

A two-color-change, nanoparticle-based method for DNA detection

YC Cao, R Jin, CS Thaxton, CA Mirkin - Talanta, 2005 - Elsevier
Herein, we describe the detailed synthesis of Ag/Au core-shell nanoparticles, the surface-
functionalization of these particles with thiolated oligonucleotides, and their subsequent use …

Colorimetric detection of DNA sequences based on electrostatic interactions with unmodified gold nanoparticles

H Li, L Rothberg - Proceedings of the National Academy of …, 2004 - National Acad Sciences
We find that single-and double-stranded oligonucleotides have different propensities to
adsorb on gold nanoparticles in colloidal solution. We use this observation to design a …

DNA-modified core− shell Ag/Au nanoparticles

Cao, R Jin, CA Mirkin - Journal of the American Chemical Society, 2001 - ACS Publications
In 1996, we reported a method for utilizing biomolecules, such as DNA, and their molecular
recognition properties to guide the assembly of nanoparticle building blocks modified with …

The structural characterization of oligonucleotide-modified gold nanoparticle networks formed by DNA hybridization

SJ Park, AA Lazarides, JJ Storhoff… - The Journal of …, 2004 - ACS Publications
The structural properties of DNA-linked gold nanoparticle materials were examined using
synchrotron small-angle X-ray scattering. The materials are composed of 12 or 19 nm …

End-to-end self-assembly and colorimetric characterization of gold nanorods and nanospheres via oligonucleotide hybridization

B Pan, L Ao, F Gao, H Tian, R He, D Cui - Nanotechnology, 2005 - iopscience.iop.org
We report end-to-end assembly for tuning the optical properties of a gold nanorod/sphere
based on oligonucleotide hybridization. The rationale behind the selection of the …

Improving colorimetric assays through protein enzyme-assisted gold nanoparticle amplification

X Xie, W Xu, X Liu - Accounts of Chemical Research, 2012 - ACS Publications
The discovery of the DNA-mediated assembly of gold nanoparticles was a great moment in
the history of science; this understanding and chemical control enabled the rational design …

“Three-Dimensional hybridization” with polyvalent DNA− Gold nanoparticle conjugates

SJ Hurst, HD Hill, CA Mirkin - Journal of the American Chemical …, 2008 - ACS Publications
We have determined the minimum number of base pairings necessary to stabilize DNA− Au
NP aggregates as a function of salt concentration for particles between 15 and 150 nm in …

Oriented gold nanoparticle aggregation for colorimetric sensors with surprisingly high analytical figures of merit

L Guo, Y Xu, AR Ferhan, G Chen… - Journal of the American …, 2013 - ACS Publications
The common drawbacks of current colorimetric sensors using gold nanoparticle aggregation
is its relatively low sensitivity and narrow dynamic range, which restrict their application in …