Extracellular vesicles as therapeutic resources in the clinical environment

J Sanz-Ros, C Mas-Bargues, N Romero-García… - International journal of …, 2023 - mdpi.com
The native role of extracellular vesicles (EVs) in mediating the transfer of biomolecules
between cells has raised the possibility to use them as therapeutic vehicles. The …

Mesenchymal stem cell-derived exosomes exhibit promising potential for treating SARS-CoV-2-infected patients

A Raghav, ZA Khan, VK Upadhayay, P Tripathi… - Cells, 2021 - mdpi.com
The novel coronavirus severe acute respiratory syndrome-CoV-2 (SARS-CoV-2) is
responsible for COVID-19 infection. The COVID-19 pandemic represents one of the worst …

Mesenchymal stem cells and their derived exosomes to combat Covid–19

M Yousefi Dehbidi, N Goodarzi… - Reviews in Medical …, 2022 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is causing an ongoing
pandemic of coronavirus disease 2019 (Covid‐19). Effective therapies are required for the …

Multifunctional role of exosomes in viral diseases: From transmission to diagnosis and therapy

P Chaudhari, V Ghate, M Nampoothiri, S Lewis - Cellular signalling, 2022 - Elsevier
Efforts to discover antiviral drugs and diagnostic platforms have intensified to an
unprecedented level since the outbreak of COVID-19. Nano-sized endosomal vesicles …

Boosting extracellular vesicle secretion

L Debbi, S Guo, D Safina, S Levenberg - Biotechnology advances, 2022 - Elsevier
In recent years, extracellular vesicles (EVs), specifically exosomes, have emerged as a
promising strategy for treating a wide spectrum of pathologies, such as cancer and COVID …

[HTML][HTML] Mesenchymal stem cell-derived exosomes for COVID-19 therapy, preclinical and clinical evidence

N Kiaie, SPM Ghanavati, SS Miremadi… - … Journal of Stem …, 2021 - synapse.koreamed.org
Since the emergence of the novel coronavirus, named COVID-19, researchers are looking
for a treatment to stop the devastating pandemic. During these efforts, mesenchymal stem …

A novel nano therapeutic using convalescent plasma derived exosomal (CPExo) for COVID-19: A combined hyperactive immune modulation and diagnostics

K Anand, C Vadivalagan, JS Joseph, SK Singh… - Chemico-Biological …, 2021 - Elsevier
Extracellular vesicles like exosomes are important therapeutic tactics for treating COVID-19.
By utilizing convalescent plasma derived exosomes (CP Exo) from COVID-19 recovered …

Could Mesenchymal stem cell-derived exosomes be a therapeutic option for critically ill COVID-19 patients?

C Gardin, L Ferroni, JC Chachques… - Journal of Clinical …, 2020 - mdpi.com
Coronavirus disease 2019 (COVID-19) is a pandemic viral disease originated in Wuhan,
China, in December 2019, caused by the severe acute respiratory syndrome coronavirus 2 …

The significance of phenotyping and quantification of plasma extracellular vesicles levels using high-sensitivity flow cytometry during COVID-19 treatment

I Kudryavtsev, O Kalinina, V Bezrukikh, O Melnik… - Viruses, 2021 - mdpi.com
New investigation results point to the potential participation of extracellular vesicles (EVs) in
the pathogenesis of coronavirus infection, its progression, and mechanisms of the therapy …

Protective role of engineered extracellular vesicles loaded quercetin nanoparticles as anti-viral therapy against SARS-CoV-2 infection: A prospective review

A Raghav, R Giri, S Agarwal, S Kala… - Frontiers in …, 2022 - frontiersin.org
Quercetin (QCT) is a naturally occurring phenolic flavonoid compound with inbuilt
characteristics of antioxidant, anti-inflammatory, and immune protection. Several recent …