[HTML][HTML] Potential application of mesenchymal stem cells and their exosomes in lung injury: an emerging therapeutic option for COVID-19 patients

S Al-Khawaga, EM Abdelalim - Stem cell research & therapy, 2020 - Springer
The COVID-19 pandemic has negatively impacted the global public health and the
international economy; therefore, there is an urgent need for an effective therapy to treat …

[HTML][HTML] Extracellular vesicle-based Nanotherapeutics: Emerging frontiers in anti-inflammatory therapy

TT Tang, B Wang, LL Lv, BC Liu - Theranostics, 2020 - ncbi.nlm.nih.gov
Dysregulated inflammation is a complicated pathological process involved in various
diseases, and the treatment of inflammation-linked disorders currently represents an …

[HTML][HTML] Proposed mechanisms of targeting COVID-19 by delivering mesenchymal stem cells and their exosomes to damaged organs

E Jamshidi, A Babajani, P Soltani… - Stem Cell Reviews and …, 2021 - Springer
With the outbreak of coronavirus disease (COVID-19) caused by novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), the world has been facing an …

[HTML][HTML] Insights into CD24 and exosome physiology and potential role in view of recent advances in COVID-19 therapeutics: a narrative review

G Tsioulos, I Grigoropoulos, CD Moschopoulos… - Life, 2022 - mdpi.com
Cluster of differentiation (CD) 24, a long-known protein with multifaceted functions, has
gained attention as a possible treatment for Coronavirus Disease 19 (COVID-19) due to its …

[HTML][HTML] Mesenchymal stem cell-based therapy and exosomes in COVID-19: current trends and prospects

M Abdelgawad, NS Bakry, AA Farghali… - Stem cell research & …, 2021 - Springer
Abstract Novel coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory
syndrome coronavirus-2. The virus causes an exaggerated immune response, resulting in a …

[HTML][HTML] Extracellular vesicles as bioactive nanotherapeutics: an emerging paradigm for regenerative medicine

M Li, F Fang, M Sun, Y Zhang, M Hu, J Zhang - Theranostics, 2022 - ncbi.nlm.nih.gov
In recent decades, extracellular vesicles (EVs), as bioactive cell-secreted nanoparticles
which are involved in various physiological and pathological processes including cell …

[HTML][HTML] ACE2‐enriched extracellular vesicles enhance infectivity of live SARS‐CoV‐2 virus

SK Tey, H Lam, SWK Wong, H Zhao… - Journal of …, 2022 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are nanoscale vesicles naturally released from cells that are
delimited by a lipid bilayer and cannot replicate (Van Niel et al., 2018). Growing evidence …

Mesenchymal stromal cells and their secreted extracellular vesicles as therapeutic tools for COVID-19 pneumonia?

M Muraca, A Pessina, M Pozzobon, M Dominici… - Journal of Controlled …, 2020 - Elsevier
The COVID-19 epidemic represents an unprecedented global health emergency, further
aggravated by the lack of effective therapies. For this reason, several clinical trials are …

Extracellular vesicles: Emerging anti-cancer drugs and advanced functionalization platforms for cancer therapy

M Wu, M Wang, H Jia, P Wu - Drug Delivery, 2022 - Taylor & Francis
Increasing evidences show that unmodified extracellular vesicles (EVs) derived from various
cells can effectively inhibit the malignant progression of different types of tumors by …

Mesenchymal stem cell derived extracellular vesicles: promising immunomodulators against autoimmune, autoinflammatory disorders and SARS-CoV-2 infection

O Bulut, I GÜrsel - Turkish Journal of Biology, 2020 - journals.tubitak.gov.tr
Discovery of novel and broad-acting immunomodulators is of critical importance for the
prevention and treatment of disorders occurring due to overexuberant immune …