[HTML][HTML] COVID-19 cytokine storm: targeting the appropriate cytokine

RQ Cron - The Lancet Rheumatology, 2021 - thelancet.com
As of January, 2021, nearly 2-million deaths worldwide have been attributed to COVID-19,
which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Much …

[HTML][HTML] The conundrum of interleukin-6 blockade in COVID-19

C Campochiaro, L Dagna - The Lancet Rheumatology, 2020 - thelancet.com
Since the very first cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection were identified in China, patients with severe manifestations of COVID-19 have …

COVACTA trial raises questions about tocilizumab's benefit in COVID-19

B Furlow - The Lancet Rheumatology, 2020 - thelancet.com
Hoffmann-La Roche has announced disappointing results from its much-anticipated phase 3
COVACTA trial of tocilizumab, raising questions about the efficacy of interleukin (IL)-6 …

[HTML][HTML] Rheumatic disease and COVID-19: initial data from the COVID-19 Global Rheumatology Alliance provider registries

MA Gianfrancesco, KL Hyrich, L Gossec… - The Lancet …, 2020 - thelancet.com
Individuals with inflammatory rheumatic disease require special consideration with regard to
coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome …

Effect of the COVID-19 pandemic on patients with systemic rheumatic diseases

A Antonelli, P Fallahi, G Elia, F Ragusa… - The Lancet …, 2021 - thelancet.com
Comment e676 www. thelancet. com/rheumatology Vol 3 October 2021 8375 [90· 1%]
women and 893 [9· 6%] men) between April 3 and May 8, 2020. The most frequent …

[HTML][HTML] Canakinumab in a subgroup of patients with COVID-19

C Ucciferri, A Auricchio, M Di Nicola… - The Lancet …, 2020 - thelancet.com
In a subgroup of patients, severe acute respiratory syndrome corona virus 2 (SARSCoV2)
induces a hyper inflammatory response that leads to acute respiratory dis tress syndrome. 1 …

[HTML][HTML] Coronavirus is the trigger, but the immune response is deadly

RQ Cron - The Lancet Rheumatology, 2020 - thelancet.com
As of mid-April, 2020, severe acute respiratory syn drome coronavirus 2 (SARS-CoV-2), the
coronavirus respon sible for COVID-19, has infected more than 4· 4 million people …

Non-steroidal anti-inflammatory drug use in COVID-19

K Kragholm, C Torp-Pedersen, E Fosbol - The Lancet Rheumatology, 2021 - thelancet.com
Early in the COVID-19 pandemic, there was concern in the media that the use of non-
steroidal antiinflammatory drugs (NSAIDs), particularly ibuprofen, might exacerbate COVID …

[HTML][HTML] Incident systemic rheumatic disease following COVID-19

TYT Hsu, KM D'Silva, NJ Patel, X Fu… - The Lancet …, 2021 - thelancet.com
Although viruses can induce rheumatic diseases, the impact of SARS-CoV-2, the virus
behind COVID-19, on the development of systemic rheumatic disease is unclear. COVID-19 …

[HTML][HTML] Patients with rheumatic diseases adhere to COVID-19 isolation measures more strictly than the general population

F Hooijberg, L Boekel, EH Vogelzang… - The Lancet …, 2020 - thelancet.com
There is a continuous debate about the risks of increased incidence of COVID-19 in
vulnerable patient groups, which includes patients with rheumatic diseases and especially …