Human natural killer (NK) cells are innate lymphoid cells that mediate important effector
functions in the control of viral infection and malignancy. Their ability to distinguish" self" …

Killer cell immunoglobulin-like receptors (KIR) are expressed on natural killer (NK) cells and
subsets of T cells. The KIR genes are polymorphic and the KIR gene complex is polygenic …

Epidemiological studies have associated certain human disease outcomes with particular
killer cell Ig-like receptor (KIR) and HLA genotypes. However, the functional explanation for …

NK cells use a variety of germline-encoded cell surface receptors to discriminate target cells
from the healthy cells. Killer cell immunoglobulin-like receptors (KIR) are the key receptors …

Killer immunoglobulin-like receptor (KIR) recognition of specific human histocompatibility
leukocyte antigen (HLA) class I allotypes contributes to the array of receptor–ligand …

Natural killer (NK) cells are lymphocytes that have vital functions in innate and adaptive
immunity, as well as placental reproduction. Polymorphic human leukocyte antigen (HLA) …

Natural killer (NK) cells represent a critical defense against viral infections and cancers. NK
cells require integration of activating and inhibitory NK cell receptors to detect target cells …

Natural Killer (NK) cells are innate lymphocytes playing pivotal roles in host defense and
immune-surveillance. The homeostatic modulation of germ-line encoded/non-rearranged …

The innate immune system is the first line of defence in response to pathogen infection.
Natural killer (NK) cells perform a vital role in this response with the ability to directly kill …

A key feature of human natural killer (NK) cells, which enables efficient recognition of
infected and malignant target cells, is the expression of HLA class I-specific receptors of the …