[HTML][HTML] GWAS Central: a comprehensive resource for the comparison and interrogation of genome-wide association studies

T Beck, RK Hastings, S Gollapudi, RC Free… - European journal of …, 2014 - nature.com
To facilitate broad and convenient integrative visualization of and access to GWAS data, we
have created the GWAS Central resource (http://www. gwascentral. org). This database …

GWAS Central: a comprehensive resource for the discovery and comparison of genotype and phenotype data from genome-wide association studies

T Beck, T Shorter, AJ Brookes - Nucleic acids research, 2020 - academic.oup.com
The GWAS Central resource provides a toolkit for integrative access and visualization of a
uniquely extensive collection of genome-wide association study data, while ensuring safe …

GWAS Central: an expanding resource for finding and visualising genotype and phenotype data from genome-wide association studies

T Beck, T Rowlands, T Shorter… - Nucleic Acids …, 2023 - academic.oup.com
The GWAS Central resource gathers and curates extensive summary-level genome-wide
association study (GWAS) data and puts a range of user-friendly but powerful website tools …

Boosting the power of genome-wide association studies within and across ancestries by using polygenic scores

AI Campos, S Namba, SC Lin, K Nam, J Sidorenko… - Nature Genetics, 2023 - nature.com
Genome-wide association studies (GWASs) have been mostly conducted in populations of
European ancestry, which currently limits the transferability of their findings to other …

[HTML][HTML] Genome-wide association studies

E Uffelmann, QQ Huang, NS Munung… - Nature Reviews …, 2021 - nature.com
Genome-wide association studies (GWAS) test hundreds of thousands of genetic variants
across many genomes to find those statistically associated with a specific trait or disease …

The NHGRI-EBI GWAS Catalog: knowledgebase and deposition resource

E Sollis, A Mosaku, A Abid, A Buniello… - Nucleic acids …, 2023 - academic.oup.com
Abstract The NHGRI-EBI GWAS Catalog (www. ebi. ac. uk/gwas) is a FAIR knowledgebase
providing detailed, structured, standardised and interoperable genome-wide association …

The UK Biobank: a shining example of genome-wide association study science with the power to detect the murky complications of real-world epidemiology

VY Tan, NJ Timpson - Annual review of genomics and human …, 2022 - annualreviews.org
Genome-wide association studies (GWASs) have successfully identified thousands of
genetic variants that are reliably associated with human traits. Although GWASs are …

[PDF][PDF] Prioritizing GWAS results: a review of statistical methods and recommendations for their application

RM Cantor, K Lange, JS Sinsheimer - The American Journal of Human …, 2010 - cell.com
Genome-wide association studies (GWAS) have rapidly become a standard method for
disease gene discovery. A substantial number of recent GWAS indicate that for most …

[HTML][HTML] Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study

CS Carlson, TC Matise, KE North, CA Haiman… - PLoS …, 2013 - journals.plos.org
The vast majority of genome-wide association study (GWAS) findings reported to date are
from populations with European Ancestry (EA), and it is not yet clear how broadly the genetic …

[HTML][HTML] 15 years of genome-wide association studies and no signs of slowing down

RJF Loos - Nature communications, 2020 - nature.com
Over the past 15 years, genome-wide association studies (GWASs) have generated a
wealth of new information. Larger samples sizes, refined phenotypes and higher-resolution …