Cytokine storm in COVID-19: immunopathogenesis and therapy
C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
A cytokine storm is a hyperinflammatory state secondary to the excessive production of
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …
[HTML][HTML] Inflammation in COVID-19: from pathogenesis to treatment
RSY Wong - International journal of clinical and experimental …, 2021 - ncbi.nlm.nih.gov
Abstract The coronavirus disease 2019 (COVID-19) was declared a pandemic in March
2020 by the World Health Organization (WHO). To date, there were> 163 million confirmed …
2020 by the World Health Organization (WHO). To date, there were> 163 million confirmed …
Hyperinflammatory response in COVID-19: a systematic review
MJA Silva, LR Ribeiro, MIM Gouveia, BR Marcelino… - Viruses, 2023 - mdpi.com
COVID-19 is a multisystemic disease caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). The immunopathogenic conditions of the hyperinflammatory …
coronavirus 2 (SARS-CoV-2). The immunopathogenic conditions of the hyperinflammatory …
Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment
COVID-19 infection has a heterogenous disease course; it may be asymptomatic or causes
only mild symptoms in the majority of the cases, while immunologic complications such as …
only mild symptoms in the majority of the cases, while immunologic complications such as …
Interleukin 6, soluble interleukin 2 receptor alpha (CD25), monocyte colony-stimulating factor, and hepatocyte growth factor linked with systemic hyperinflammation …
L Quartuccio, M Fabris, A Sonaglia, M Peghin… - Cytokine, 2021 - Elsevier
Background Patients infected by SARS-CoV-2 can develop interstitial pneumonia, requiring
hospitalisation or mechanical ventilation. Increased levels of inflammatory biomarkers are …
hospitalisation or mechanical ventilation. Increased levels of inflammatory biomarkers are …
[HTML][HTML] COVID-19 and the immune system
J Paces, Z Strizova, S Daniel, J Cerny - Physiological research, 2020 - ncbi.nlm.nih.gov
A close interaction between the virus SARS-CoV-2 and the immune system of an individual
results in a diverse clinical manifestation of the COVID-19 disease. While adaptive immune …
results in a diverse clinical manifestation of the COVID-19 disease. While adaptive immune …
The role and therapeutic potential of NF-kappa-B pathway in severe COVID-19 patients
A Hariharan, AR Hakeem, S Radhakrishnan… - …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) pandemic has affected health care systems
worldwide. Severe presentations of COVID-19 such as severe pneumonia and acute …
worldwide. Severe presentations of COVID-19 such as severe pneumonia and acute …
T cell activation, highly armed cytotoxic cells and a shift in monocytes CD300 receptors expression is characteristic of patients with severe COVID-19
O Zenarruzabeitia, G Astarloa-Pando, I Terren… - Frontiers in …, 2021 - frontiersin.org
COVID-19 manifests with a wide diversity of clinical phenotypes characterized by
dysfunctional and exaggerated host immune responses. Many results have been described …
dysfunctional and exaggerated host immune responses. Many results have been described …
The pathogenesis of coronavirus-19 disease
AC Borczuk, RK Yantiss - Journal of biomedical science, 2022 - Springer
Severe acute respiratory syndrome-associated coronavirus-2 (SARS-CoV-2) is the causal
agent of coronavirus disease-2019 (COVID-19), a systemic illness characterized by variably …
agent of coronavirus disease-2019 (COVID-19), a systemic illness characterized by variably …
[HTML][HTML] SARS-Cov-2 infection: Response of human immune system and possible implications for the rapid test and treatment
G di Mauro, C Scavone, C Rafaniello, F Rossi… - International …, 2020 - Elsevier
The new coronavirus outbreak is an ongoing pandemic that is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). The new coronavirus SARS-Cov-2 …
respiratory syndrome coronavirus 2 (SARS-CoV-2). The new coronavirus SARS-Cov-2 …