Elderly patients are the main users of drugs and they differ from younger patients. They are a
heterogeneous population that cannot be defined only by age but should rather be stratified …

The aging processes alter the body's response to a medicine's pharmacokinetics,
pharmacodynamics, and susceptibility to adverse effects. In addition, older adults, especially …

The aging process is linked to changes in the physiological function of organs and changes
in body composition that alter the pharmacokinetics of drugs and pharmacodynamic …

Polypharmacy and physiological changes inherent to the aging process can cause
significant modifications in the pharmacokinetic and dynamic regimens of drugs, making the …

In addition to being a fast-growing subpopulation, the elderly also receive large quantities of
medication and are particularly exposed to iatrogenic effects. In France, 8.6 per cent of …

Geriatric patients are a subset of older people with multiple comorbidities that usually have
significant functional implications. Geriatric patients have impaired homeostasis and wide …

Objective: To recognise and prevent ADRs (including DDIs) in the elderly through a 4-year
post-marketing active pharmacovigilance programme. The programme was designed to …

Introduction The proportion of the elderly is constantly increasing and by the year 2025 20%
of the population will be above 65 years of age. With advanced age, subjects will develop …

Adverse drug reactions (ADRs) in older adults are an important healthcare problem since
they are frequently a cause of hospitalization, occur commonly during admission, and are an …

Adverse drug reactions (ADRs) are common in older adults, with falls, orthostatic
hypotension, delirium, renal failure, gastrointestinal and intracranial bleeding being amongst …