Background Pairing of homologous chromosomes at meiosis is an important requirement for recombination and balanced chromosome segregation among the products of meiotic …
JL Gerton, JL DeRisi - … of the National Academy of Sciences, 2002 - National Acad Sciences
We used a functional genomics approach to identify a gene required for meiotic recombination, YGL183c or MND1. MND1 was spliced in meiotic cells, extending the …
H Tsubouchi, GS Roeder - Molecular and cellular biology, 2002 - Taylor & Francis
The hop2 mutant of Saccharomyces cerevisiae arrests in meiosis with extensive synaptonemal complex (SC) formation between nonhomologous chromosomes. A screen …
JM Henry, R Camahort, DA Rice, L Florens… - … and cellular biology, 2006 - Taylor & Francis
During meiosis, each chromosome must pair with its homolog and undergo meiotic crossover recombination in order to segregate properly at the first meiotic division …
S Domenichini, C Raynaud, DA Ni, Y Henry… - DNA repair, 2006 - Elsevier
The efficient repair of double-strand breaks (DSBs) in genomic DNA is crucial for the survival of all organisms. Mnd1 is suggested to promote the strand invasion step during meiotic …
F Couteau, F Belzile, C Horlow, O Grandjean… - The Plant …, 1999 - academic.oup.com
In yeast, the DMC1 gene is required for interhomolog recombination, which is an essential step for bivalent formation and the correct partition of chromosomes during meiosis I. By …
YK Chen, CH Leng, H Olivares… - Proceedings of the …, 2004 - National Acad Sciences
Saccharomyces cerevisiae Hop2 and Mnd1 are abundant meiosisspecific chromosomal proteins, and mutations in the corresponding genes lead to defects in meiotic recombination …
Background: While double-strand break (DSB) repair is vital to the survival of cells during both meiosis and mitosis, the preferred mechanism of repair differs drastically between the …
MSH5, a meiosis‐specific member of the MutS‐homologue family of genes, is required for normal levels of recombination in budding yeast, mouse and Caenorhabditis elegans. In this …