The Arabidopsis thaliana MND1 homologue plays a key role in meiotic homologous pairing, synapsis and recombination

C Kerzendorfer, J Vignard… - Journal of Cell …, 2006 - journals.biologists.com
Mnd1 has recently been identified in yeast as a key player in meiotic recombination. Here
we describe the identification and functional characterisation of the Arabidopsis homologue …

AtMND1 is required for homologous pairing during meiosis in Arabidopsis

AP Panoli, M Ravi, J Sebastian, B Nishal… - BMC Molecular …, 2006 - Springer
Background Pairing of homologous chromosomes at meiosis is an important requirement for
recombination and balanced chromosome segregation among the products of meiotic …

Mnd1p: an evolutionarily conserved protein required for meiotic recombination

JL Gerton, JL DeRisi - … of the National Academy of Sciences, 2002 - National Acad Sciences
We used a functional genomics approach to identify a gene required for meiotic
recombination, YGL183c or MND1. MND1 was spliced in meiotic cells, extending the …

The Mnd1 protein forms a complex with hop2 to promote homologous chromosome pairing and meiotic double-strand break repair

H Tsubouchi, GS Roeder - Molecular and cellular biology, 2002 - Taylor & Francis
The hop2 mutant of Saccharomyces cerevisiae arrests in meiosis with extensive
synaptonemal complex (SC) formation between nonhomologous chromosomes. A screen …

Mnd1/Hop2 facilitates Dmc1-dependent interhomolog crossover formation in meiosis of budding yeast

JM Henry, R Camahort, DA Rice, L Florens… - … and cellular biology, 2006 - Taylor & Francis
During meiosis, each chromosome must pair with its homolog and undergo meiotic
crossover recombination in order to segregate properly at the first meiotic division …

Atmnd1-Δ1 is sensitive to gamma-irradiation and defective in meiotic DNA repair

S Domenichini, C Raynaud, DA Ni, Y Henry… - DNA repair, 2006 - Elsevier
The efficient repair of double-strand breaks (DSBs) in genomic DNA is crucial for the survival
of all organisms. Mnd1 is suggested to promote the strand invasion step during meiotic …

Random Chromosome Segregation without Meiotic Arrest in Both Male and Female Meiocytes of a dmc1 Mutant of Arabidopsis

F Couteau, F Belzile, C Horlow, O Grandjean… - The Plant …, 1999 - academic.oup.com
In yeast, the DMC1 gene is required for interhomolog recombination, which is an essential
step for bivalent formation and the correct partition of chromosomes during meiosis I. By …

Heterodimeric complexes of Hop2 and Mnd1 function with Dmc1 to promote meiotic homolog juxtaposition and strand assimilation

YK Chen, CH Leng, H Olivares… - Proceedings of the …, 2004 - National Acad Sciences
Saccharomyces cerevisiae Hop2 and Mnd1 are abundant meiosisspecific chromosomal
proteins, and mutations in the corresponding genes lead to defects in meiotic recombination …

Mnd1 is required for meiotic interhomolog repair

C Zierhut, M Berlinger, C Rupp, A Shinohara, F Klein - Current Biology, 2004 - cell.com
Background: While double-strand break (DSB) repair is vital to the survival of cells during
both meiosis and mitosis, the preferred mechanism of repair differs drastically between the …

AtMSH5 partners AtMSH4 in the class I meiotic crossover pathway in Arabidopsis thaliana, but is not required for synapsis

JD Higgins, J Vignard, R Mercier, AG Pugh… - The Plant …, 2008 - Wiley Online Library
MSH5, a meiosis‐specific member of the MutS‐homologue family of genes, is required for
normal levels of recombination in budding yeast, mouse and Caenorhabditis elegans. In this …