Self-Controlled Case Series Studies: A Modelling Guide with R provides the first
comprehensive account of the self-controlled case series (SCCS) method, a statistical …

The self controlled case series (SCCS) method is an epidemiological study design for which
individuals act as their own control—ie, comparisons are made within individuals. Hence …

The self‐controlled case series method was developed to investigate associations between
acute outcomes and transient exposures, using only data on cases, that is, on individuals …

We describe some simple techniques for investigating 2 key assumptions of the self‐
controlled case series (SCCS) method, namely, that events do not influence subsequent …

Background Despite the frequent use of self-controlled methods in
pharmacoepidemiological studies, the factors that may bias the estimates from these …

We derive several formulae for the sample size required for a study designed using the self‐
controlled case series method without age effects. We investigate these formulae by …

The self-controlled case-series method was originally developed to investigate potential
associations between vaccines and adverse events, and is now commonly used for this …

The self-controlled case series method is increasingly being used in pharmacoepidemiology
, particularly in vaccine safety studies. This method is typically used to evaluate the …

Background The self-controlled case series (SCCS) offers potential as an statistical method
for risk identification involving medical products from large-scale observational healthcare …

Self‐controlled observational study designs, such as the case–crossover design and the self‐
controlled case series, are reviewed, and their respective rationale, strengths and limitations …