Hyperthermia is a promising anticancer treatment used in combination with radiotherapy
and chemotherapy. Temperatures above 41.5° C are cytotoxic and hyperthermia treatments …

Autophagy is an evolutionarily conserved process for bulk degradation of cytoplasmic
components, including large molecules and organelles. It can either help to enhance or to …

Under conditions of extreme heat stress, the process of autophagy has previously been
shown to protect human cells, but the exact body temperature at which autophagic activation …

The purpose of this study was to evaluate the mechanism of ROS‐induced hyperthermic cell
death in a colon cancer cell line. HT‐29 colon cancer cells were exposed to heat (43° C) in …

Purpose: The pleiotropic effects of heat on cancer cells have been well documented. The
biological effects seen depend on the temperature applied, and the heating duration. In this …

Objective: To establish a model of incomplete ablation in nude mice with hepatocellular
carcinoma (HCC) and to evaluate heat shock protein (HSP) expression and autophagy and …

Various toxic compounds produce reactive oxygen species, resulting in oxidative stress that
threatens cellular homeostasis. Yet, lower doses of stress can stimulate defence systems …

Temperature variations in cells, tissues and organs may occur in a number of circumstances.
We report here that reducing temperature of cells in culture to 25° C for 5 days followed by a …

The occurrence and mechanisms of autophagy induced by heat stress are not well known in
lung cancer cells. Here, we have demonstrated that heat stress induces autophagy in A549 …

Hypothermia is a critical consequence of extreme cold exposure that increases the risk of
cold-related injury and death in humans. While the initiation of cytoprotective mechanisms …