Complex immune deregulation in severe COVID-19: More than a mechanism of pathogenesis

EJ Giamarellos-Bourboulis - EBioMedicine, 2021 - thelancet.com
The generated impression early at the beginning of the pandemic by SARS-CoV-2 (also
called COVID-19) was that severe COVID-19 is due to a cytokine storm with the over …

Severe COVID-19 is characterized by the co-occurrence of moderate cytokine inflammation and severe monocyte dysregulation

B Bonnet, J Cosme, C Dupuis, E Coupez, M Adda… - …, 2021 - thelancet.com
Background SARS-CoV-2 has been responsible for considerable mortality worldwide, owing
in particular to pulmonary failures such as ARDS, but also to other visceral failures and …

COVID-19: towards understanding of pathogenesis

W Cao, T Li - Cell research, 2020 - nature.com
The pandemic of coronavirus disease 2019 (COVID-19) is spreading rapidly. Although the
cause was quickly identified as a new coronavirus named SARS-CoV-2, our knowledge of …

A glimpse into the eye of the COVID-19 cytokine storm

K Kuppalli, AL Rasmussen - EBioMedicine, 2020 - thelancet.com
The pathogenesis of pandemic coronavirus disease-2019 (COVID-19) caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) likely depends heavily on …

Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
A cytokine storm is a hyperinflammatory state secondary to the excessive production of
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …

[PDF][PDF] Dysregulation of the immune system as a driver of the critical course of novel coronavirus disease 2019

A Kosmaczewska, I Frydecka - Pol Arch Intern Med, 2020 - scholar.archive.org
AbsTRACT Novel coronavirus disease 2019 (COVID‑19) is a highly contagious, respiratory
disease caused by the newly emerged severe acute respiratory syndrome coronavirus 2 …

Cytokine storm may not be the chief culprit for the deterioration of COVID-19

Y Gao, C Wang, K Kang, Y Peng, Y Luo, H Liu… - Viral …, 2021 - liebertpub.com
COVID-19 is spreading and ravaging all over the world, and the number of deaths is
increasing day by day without downward trend. However, there is limited knowledge of …

Tackling the cytokine storm in COVID-19, challenges and hopes

SM Abdin, SM Elgendy, SK Alyammahi, DW Alhamad… - Life Sciences, 2020 - Elsevier
The outbreak of Coronavirus disease 2019 (COVID-19) is the current world health concern,
presenting a public health dilemma with ascending morbidity and mortality rates exceeding …

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by the virus designated as severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread widely throughout the …

[HTML][HTML] Immune Dysregulation during and after COVID-19:“Tomorrow Never Dies” Situation

S Patil, S Patil, G Gondhali… - Journal of Translational …, 2023 - journals.lww.com
Coronavirus disease 2019 (COVID-19) pandemic has been studied over last two and half
years for its highly pathogenic nature of corona virus. Main hurdle for acquiring …