CD34+ stem cells play an important role during liver development and regeneration. Thus,
we hypothesized that some human liver carcinomas (HLCs) might be derived from …

A large number of cancer stem cells (CSCs) were identified and characterized; however, the
origins and formation of CSCs remain elusive. In this study, we examined the origination of …

A large number of cancer stem cells (CSCs) have been isolated and identified; however,
none has been cultured in an unlimited manner in vitro without losing tumorigenicity and …

Background & Aims: Recent efforts in stem cell biology suggest that tumors are organized in
a hierarchy of heterogeneous cell populations and that the capability to maintain tumor …

Increasing evidence has revealed the importance of cancer stem cells (CSCs) in
carcinogenesis. Although liver CSCs have been identified in hepatocellular carcinoma …

Primary hepatocellular carcinoma (HCC) often invades into vessels and has a distal
metastasis at an early stage, resulting in poor prognosis and therapeutic outcome. The …

The CD133 antigen, identified as a hematopoietic stem cell marker, appears in various
human embryonic epithelia including the neural tube, gut, and kidney. We herein …

Cancer stem cells (CSCs) are a small subpopulation of cells within tumors with capabilities
of self-renewal, differentiation, and tumorigenicity when transplanted into immune …

Although the stem cells are commonly isolated by FACS or MACS, they are very expensive
and these is no specific marker for liver stem/progentior cells (LSPCs). This paper applied a …

Cancer stem cells (CSCs) are defined as cells within tumors that can self-renew and
differentiate into heterogeneous lineages of cancerous cells. The origin of CSCs is not well …