Visible-light-induced intermolecular dearomative cyclization of furans: synthesis of 1-oxaspiro [4.4] nona-3, 6-dien-2-one

W Dong, Y Yuan, X Gao, M Keranmu, W Li… - The Journal of …, 2019 - ACS Publications
A fac-Ir (ppy) 3-catalyzed intermolecular dearomative cyclization of 2-bromo-2-((5-
bromofuran-2-yl) methyl) malonate and alkynes affording substituted spirolactones in yields …

Visible-light-induced intermolecular dearomative cyclization of 2-bromo-1, 3-dicarbonyl compounds and alkynes: Synthesis of spiro [4.5] deca-1, 6, 9-trien-8-ones

W Dong, Y Yuan, X Gao, M Keranmu, W Li, X Xie… - Organic …, 2018 - ACS Publications
A visible-light-induced photocatalytic intermolecular dearomative cyclization of 2-bromo-1, 3-
dicarbonyl compounds and alkynes afforded biologically important spirocarbocycle …

Photocatalytic Radical Ortho-Dearomative Cyclization: Access to Spiro[4.5]deca-1,7,9-trien-6-ones

W Dong, Y Yuan, C Liang, F Wu, S Zhang… - The Journal of …, 2021 - ACS Publications
A highly efficient ortho-dearomative cyclization reaction between alkynes and 2-bromo-2-(2-
methoxybenzyl) malonate via visible light-induced photoredox catalysis has been reported …

Visible-light-driven dearomatization reaction toward the formation of spiro [4.5] deca-1, 6, 9-trien-8-ones

W Dong, Y Yuan, X Xie, Z Zhang - Organic letters, 2020 - ACS Publications
A visible-light-driven regioselective dearomative cyclization between 2-benzyl-2-
bromomalonate and alkynes under mild conditions leading to the formation of spiro [4, 5] …

Redox-Neutral Intramolecular Dearomative Spirocyclization of Phenols Induced by Visible Light

L Zhang, F Hu, L Shen, L Gao, Y Yang, Z Pan… - Organic …, 2023 - ACS Publications
Described herein is a redox-neutral intramolecular dearomative spirocyclization induced by
visible light. The photochemical cyclization was catalyzed by a phenolate anion-derived …

Visible light-induced intramolecular dearomative cyclization of α-bromo-N-benzyl-alkylamides: efficient construction of 2-azaspiro [4.5] decanes

B Hu, Y Li, W Dong, K Ren, X Xie, J Wan… - Chemical …, 2016 - pubs.rsc.org
Visible light-induced intramolecular dearomative cyclization of α-bromo- N -benzyl-alkylamides:
efficient construction of 2-azaspiro[4.5]decanes - Chemical Communications (RSC Publishing) …

Alkylative dearomatization by using an unactivated aryl nitro group as a leaving group: access to diversified alkylated spiro [5.5] trienones

D Xia, XF Duan - Organic Letters, 2021 - ACS Publications
The cleavage of an unactivated aryl nitro group triggered by alkyl radicals enables a
dearomative cyclization, affording diversified alkylated spiro [5.5] trienones in good yields …

Highly congested spiro-compounds via photoredox-mediated dearomative annulation cascade

C Zhou, A Shatskiy, AZ Temerdashev… - Communications …, 2022 - nature.com
Photo-mediated radical dearomatization involving 5-exo-trig cyclizations has proven to be
an important route to accessing spirocyclic compounds, whereas 6-exo-trig spirocyclization …

Dearomative spirocyclization via visible-light-induced reductive hydroarylation of non-activated arenes

Z Chi, Y Gao, L Yang, C Zhou, M Zhang, P Cheng… - Chinese Chemical …, 2022 - Elsevier
A visible-light-induced spirocyclizative hydroarylation via reductive dearomatization of a
series of non-activated arenes including 2-phenyl indoles and naphthalene derivatives …

Radical‐Mediated Non‐Dearomative Strategies in Construction of Spiro Compounds

R Pawlowski, P Skorka… - Advanced Synthesis & …, 2020 - Wiley Online Library
In recent years, spirocyclic compounds have attracted a significant interest in medicinal
chemistry due to their considerable biological activities. The general and widely used …